Emerging Microbes & Infections, Volume 12, Issue 1 (2023)

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Emerging Microbes & Infections, Volume 12, Issue 1 (2023)

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Coronaviruses

Article
Generation of self-replicating airway organoids from the cave nectar bat Eonycteris spelaea as a model system for studying host–pathogen interactions in the bat airway epithelium
Louisa L.Y. Chan, Akshamal M. Gamage, Chee Wah Tan, Kai Sen Tan, Jing Liu, Douglas Jie Wen Tay, Randy Jee Hiang Foo, Laurent Rénia, De Yun Wang & Lin-Fa Wang
Article: e2148561
Published online: 12 Dec 2022
AbstractforGeneration of self-replicating airway organoids from the cave nectar bat Eonycteris spelaea as a model system for studying host–pathogen interactions in the bat airway epithelium | Full Text | References | PDF (3 MB) | EPUB | Supplemental
  • 2475 Views
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Open Access
Letter
Heterologous Omicron-adapted vaccine as a secondary booster promotes neutralizing antibodies against Omicron and its sub-lineages in mice
Jianyang Liu, Qian He, Fan Gao, Lianlian Bian, Qian Wang, Chaoqiang An, Lifang Song, Jialu Zhang, Dong Liu, Ziyang Song, Lu Li, Yu Bai, Zhongfang Wang, Zhenglun Liang, Qunying Mao & Miao Xu
Article: e2143283
Published online: 12 Dec 2022
AbstractforHeterologous Omicron-adapted vaccine as a secondary booster promotes neutralizing antibodies against Omicron and its sub-lineages in mice | Full Text | References | PDF (849.3 KB) | EPUB | Supplemental
  • 1613 Views
  • 1 CrossRef citations
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Open Access
Letter
Mouse study of combined DNA/protein COVID-19 vaccine to boost high levels of antibody and cell mediated immune responses
Qian He, Shuying Liu, Zhenglun Liang, Shan Lu, Wei Cun & Qunying Mao
Article: 2152388
Published online: 12 Dec 2022
First Page PreviewforMouse study of combined DNA/protein COVID-19 vaccine to boost high levels of antibody and cell mediated immune responses | Full Text | References | PDF (917.6 KB) | EPUB | Supplemental
  • 1911 Views
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Open Access

Tuberculosis

Article
Accuracy of Xpert® MTB/RIF Ultra test for posterior oropharyngeal saliva for the diagnosis of paucibacillary pulmonary tuberculosis: a prospective multicenter study
Peijun Tang, Rongmei Liu, Lin Qin, Ping Xu, Yu Xiong, Yunfeng Deng, Zizheng Lv, Yuanyuan Shang, Xinghui Gao, Lin Yao, Ruoyu Zhang, Yanjun Feng, Caihong Ding, Hui Jing, Liang Li, Yi-Wei Tang & Yu Pang
Article: 2148564
Published online: 12 Dec 2022
AbstractforAccuracy of Xpert® MTB/RIF Ultra test for posterior oropharyngeal saliva for the diagnosis of paucibacillary pulmonary tuberculosis: a prospective multicenter study | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 1934 Views
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Open Access

Letter

Letter
The first case of monkeypox in Hong Kong presenting as infectious mononucleosis-like syndrome
Kelvin Hei-Yeung Chiu, Shuk-Ching Wong, Anthony Raymond Tam, Siddharth Sridhar, Cyril Chik-Yan Yip, Kwok-Hung Chan, Nicholas Foo-Siong Chew, Kenyon Ka-Yun Man, Wan-Mui Chan, Jonathan Daniel Ip, Allen Wing-Ho Chu, Janice Yee-Chi Lo, Ivan Fan-Ngai Hung, Kwok-Yung Yuen, Kelvin Kai-Wang To & Vincent Chi-Chung Cheng
Article: 2146910
Published online: 12 Dec 2022
First Page PreviewforThe first case of monkeypox in Hong Kong presenting as infectious mononucleosis-like syndrome | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
  • 1718 Views
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Open Access

Influenza infections

Review
Alarming situation of emerging H5 and H7 avian influenza and effective control strategies
Jianzhong Shi, Xianying Zeng, Pengfei Cui, Cheng Yan & Hualan Chen
Article: 2155072
Published online: 12 Dec 2022
AbstractforAlarming situation of emerging H5 and H7 avian influenza and effective control strategies | Full Text | References | PDF (2.3 MB) | EPUB
  • 8054 Views
  • 16 CrossRef citations
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Open Access

Coronaviruses

Article
Antibody persistence and safety after heterologous boosting with orally aerosolised Ad5-nCoV in individuals primed with two-dose CoronaVac previously: 12-month analyses of a randomized controlled trial
Lairun Jin, Rong Tang, Shipo Wu, Xiling Guo, Haitao Huang, Lihua Hou, Xiaoqin Chen, Tao Zhu, Jinbo Gou, Jin Zhong, Hongxing Pan, Lunbiao Cui, Yin Chen, Xin Xia, Jialu Feng, Xue Wang, Qi Zhao, XiaoYu Xu, Zhuopei Li, Xiaoyin Zhang, Wei Chen, Jingxin Li & Fengcai Zhu
Article: 2155251
Published online: 15 Dec 2022
AbstractforAntibody persistence and safety after heterologous boosting with orally aerosolised Ad5-nCoV in individuals primed with two-dose CoronaVac previously: 12-month analyses of a randomized controlled trial | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 4090 Views
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Open Access

Antimicrobial Agents

Article
Decreased echinocandin susceptibility in Candida parapsilosis causing candidemia and emergence of a pan-echinocandin resistant case in China
Yating Ning, Meng Xiao, David S. Perlin, Yanan Zhao, Minya Lu, Yi Li, Zhengyu Luo, Rongchen Dai, Shengjie Li, Jiajun Xu, Lingli Liu, Hong He, Yun Liu, Fushun Li, Yuguang Guo, Zhongju Chen, Yingchun Xu, Tianshu Sun & Li Zhang
Article: 2153086
Published online: 24 Dec 2022
AbstractforDecreased echinocandin susceptibility in Candida parapsilosis causing candidemia and emergence of a pan-echinocandin resistant case in China | Full Text | References | PDF (1.6 MB) | EPUB | Supplemental
  • 2662 Views
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Open Access

Review

Review
Autophagy, cell death, and cytokines in K. pneumoniae infection: therapeutic perspectives
Sha Wei, Tingting Xu, Yuxin Chen & Kai Zhou
Article: 2140607
Published online: 18 Dec 2022
AbstractforAutophagy, cell death, and cytokines in K. pneumoniae infection: therapeutic perspectives | Full Text | References | PDF (2.6 MB) | EPUB
  • 2824 Views
  • 2 CrossRef citations
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Open Access

Hepatitis

Article
Profile of clinical characteristics and serologic markers of sporadic hepatitis E in a community cohort study
Zi-Min Tang, Gui-Ping Wen, Dong Ying, Si-Ling Wang, Chang Liu, Wei-Kun Tian, Ying-Bin Wang, Mu-Jin Fang, Yu-Lin Zhou, Yun-Sheng Ge, Ting Wu, Jun Zhang, Shou-Jie Huang, Zi-Zheng Zheng & Ning-Shao Xia
Article: 2140613
Published online: 18 Dec 2022
AbstractforProfile of clinical characteristics and serologic markers of sporadic hepatitis E in a community cohort study | Full Text | References | PDF (2.7 MB) | EPUB | Supplemental
  • 1557 Views
  • 1 CrossRef citations
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Open Access

Research Article

Article
Genetic, biological and epidemiological study on a cluster of H9N2 avian influenza virus infections among chickens, a pet cat, and humans at a backyard farm in Guangxi, China
Jing Yang, Jianhua Yan, Cheng Zhang, Shanqin Li, Manhua Yuan, Chunge Zhang, Chenguang Shen, Yang Yang, Lifeng Fu, Guanlong Xu, Weifeng Shi, Zhenghai Ma, Ting Rong Luo & Yuhai Bi
Article: 2143282
Published online: 18 Dec 2022
AbstractforGenetic, biological and epidemiological study on a cluster of H9N2 avian influenza virus infections among chickens, a pet cat, and humans at a backyard farm in Guangxi, China | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 3083 Views
  • 3 CrossRef citations
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Open Access

Coronaviruses

Article
Impact of vaccination on kinetics of neutralizing antibodies against SARS-CoV-2 by serum live neutralization test based on a prospective cohort
Liguo Zhu, Naiying Mao, Changhua Yi, Aidibai Simayi, Jialu Feng, Yi Feng, Min He, Songning Ding, Yin Wang, Yan Wang, Mingwei Wei, Jie Hong, Chuchu Li, Hua Tian, Lu Zhou, Jiefu Peng, Shihan Zhang, Ci Song, Hui Jin, Fengcai Zhu, Wenbo Xu, Jun Zhao & Changjun Bao
Article: 2146535
Published online: 19 Jan 2023
AbstractforImpact of vaccination on kinetics of neutralizing antibodies against SARS-CoV-2 by serum live neutralization test based on a prospective cohort | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
  • 1680 Views
  • 1 CrossRef citations
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Open Access

Research Article

Article
African swine fever virus – variants on the rise
Jan H. Forth, Sten Calvelage, Melina Fischer, Jan Hellert, Julia Sehl-Ewert, Hanna Roszyk, Paul Deutschmann, Adam Reichold, Martin Lange, Hans-Hermann Thulke, Carola Sauter-Louis, Dirk Höper, Svitlana Mandyhra, Maryna Sapachova, Martin Beer & Sandra Blome
Article: 2146537
Published online: 22 Dec 2022
AbstractforAfrican swine fever virus – variants on the rise | Full Text | References | PDF (3 MB) | EPUB | Supplemental
  • 3308 Views
  • 8 CrossRef citations
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Open Access

Zika

Article
Offspring affected with in utero Zika virus infection retain molecular footprints in the bone marrow and blood cells
Daniel Udenze, Ivan Trus, Sean Lipsit, Scott Napper & Uladzimir Karniychuk
Article: 2147021
Published online: 20 Jan 2023
AbstractforOffspring affected with in utero Zika virus infection retain molecular footprints in the bone marrow and blood cells | Full Text | References | PDF (4 MB) | EPUB | Supplemental
  • 1685 Views
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Open Access

Research Article

Article
Transmission network and phylogenetic analysis reveal older male-centered transmission of CRF01_AE and CRF07_BC in Guangxi, China
Fei Zhang, Yao Yang, Na Liang, Huayue Liang, Yongzheng Chen, Zhaosen Lin, Tongbi Chen, Wenling Tan, Yuan Yang, Rongye Huang, Lin Yao, Fuling Chen, Xingzhen Huang, Li Ye, Hao Liang & Bingyu Liang
Article: 2147023
Published online: 28 Dec 2022
AbstractforTransmission network and phylogenetic analysis reveal older male-centered transmission of CRF01_AE and CRF07_BC in Guangxi, China | Full Text | References | PDF (2 MB) | EPUB | Supplemental
  • 1394 Views
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Open Access

Letter

Letter
Bordetella hinzii bacteremia in a patient with SARS-CoV-2 infection
Kamilia Chahi, Christine Collienne, Ahalieyah Anantharajah, Hector Rodriguez-Villalobos & Philippe Hantson
Article: 2147276
Published online: 20 Dec 2022
First Page PreviewforBordetella hinzii bacteremia in a patient with SARS-CoV-2 infection | Full Text | References | PDF (381.8 KB) | EPUB
  • 1320 Views
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Open Access

Research Article

Article
Evaluation of an I177L gene-based five-gene-deleted African swine fever virus as a live attenuated vaccine in pigs
Yingnan Liu, Zhenhua Xie, Yao Li, Yingying Song, Dongdong Di, Jingyi Liu, Lang Gong, Zongyan Chen, Jinxian Wu, Zhengqin Ye, Jianqi Liu, Wanqi Yu, Lu Lv, Qiuping Zhong, Chuanwen Tian, Qingqing Song, Heng Wang & Hongjun Chen
Article: 2148560
Published online: 18 Dec 2022
AbstractforEvaluation of an I177L gene-based five-gene-deleted African swine fever virus as a live attenuated vaccine in pigs | Full Text | References | PDF (3.6 MB) | EPUB
  • 2886 Views
  • 6 CrossRef citations
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Open Access

Antimicrobial Agents

Article
Epidemiological characteristics and molecular features of carbapenem-resistant Enterobacter strains in China: a multicenter genomic study
Zhichen Zhu, Xiaofang Xie, Hua Yu, Wei Jia, Bin Shan, Bin Huang, Fen Qu, Siqiang Niu, Jinnan Lv, Qizhao Gao, Feinan Qian, Xiangxiang Tian, Yaxuan Zhai, Yicheng Wen, Chengcheng Yang, Jie Zhu, Yiwei Tang, Liang Chen & Hong Du
Article: 2148562
Published online: 19 Dec 2022
AbstractforEpidemiological characteristics and molecular features of carbapenem-resistant Enterobacter strains in China: a multicenter genomic study | Full Text | References | PDF (5 MB) | EPUB | Supplemental
  • 2238 Views
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Open Access

Letter

Letter
Place of magistral preparations to continue the treatment if the drug is commercially stopped worldwide? A case report of a 10-year-old child with subacute sclerosing panencephalitis (SSPE) requiring inosiplex
Renan Le Cras, Roseline Mazet, Fanny Dubois-Teklali, Cécile Sabourdy, Sébastien Chanoine, Audrey Lehmann, Agathe Morin, Julien Leenhardt, Marjorie Durand, Marie-Dominique Desruet & Pierrick Bedouch
Article: 2148563
Published online: 20 Dec 2022
AbstractforPlace of magistral preparations to continue the treatment if the drug is commercially stopped worldwide? A case report of a 10-year-old child with subacute sclerosing panencephalitis (SSPE) requiring inosiplex | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 1406 Views
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Open Access
Letter
Transmission of recombinant enterovirus A76 (EV-A76) in Xinjiang Uighur autonomous region of China
Xiaolei Li, Huanhuan Lu, Qiang Sun, Peng Zheng, Bo Zhang, Hui Cui, Haishu Tang, Hehe Zhao, Ying Liu, Jie Jiang, Jinbo Xiao & Yong Zhang
Article: 2149350
Published online: 20 Dec 2022
AbstractforTransmission of recombinant enterovirus A76 (EV-A76) in Xinjiang Uighur autonomous region of China | Full Text | References | PDF (1,008.1 KB) | EPUB | Supplemental
  • 1487 Views
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Open Access

Non-Neutralizing Protective Antibodies

Article
Non-neutralizing monoclonal antibody targeting VP2 EF loop of Coxsackievirus A16 can protect mice from lethal attack via Fc-dependent effector mechanism
Ruixiao Du, Chaoqiang An, Xin Yao, Yiping Wang, Ge Wang, Fan Gao, Lianlian Bian, Yalin Hu, Siyuan Liu, Qiaohui Zhao, Qunying Mao & Zhenglun Liang
Article: 2149352
Published online: 20 Dec 2022
AbstractforNon-neutralizing monoclonal antibody targeting VP2 EF loop of Coxsackievirus A16 can protect mice from lethal attack via Fc-dependent effector mechanism | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
  • 1575 Views
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Open Access

Coronaviruses

Article
A receptor-binding domain-based nanoparticle vaccine elicits durable neutralizing antibody responses against SARS-CoV-2 and variants of concern
I-Jung Lee, Yu-Hua Lan, Ping-Yi Wu, Yan-Wei Wu, Yu-Hung Chen, Sheng-Che Tseng, Tzu-Jiun Kuo, Cheng-Pu Sun, Jia-Tsrong Jan, Hsiu-Hua Ma, Chun-Che Liao, Jian-Jong Liang, Hui-Ying Ko, Chih-Shin Chang, Wen-Chun Liu, Yi-An Ko, Yen-Hui Chen, Zong-Lin Sie, Szu-I Tsung, Yi-Ling Lin, I-Hsuan Wang & Mi-Hua Tao
Article: 2149353
Published online: 24 Dec 2022
AbstractforA receptor-binding domain-based nanoparticle vaccine elicits durable neutralizing antibody responses against SARS-CoV-2 and variants of concern | Full Text | References | PDF (3 MB) | EPUB
  • 2712 Views
  • 3 CrossRef citations
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Open Access
Article
Effectiveness of inactivated COVID-19 vaccines against mild disease, pneumonia, and severe disease among persons infected with SARS-CoV-2 Omicron variant: real-world study in Jilin Province, China
Hongqin Xu, Hongyan Li, Hailong You, Peng Zhang, Nan Li, Nan Jiang, Yang Cao, Ling Qin, Guixiang Qin, Hongbo Qu, Heyuan Wang, Bo Zou, Xia He, Dan Li, Huazhong Zhao, Gang Huang, Yang Li, Hefeng Zhang, Liping Zhu, Hongmei Qiao, Hongjun Li, Shurong Liu, Lina Gu, Guidong Yin, Ye Hu, Songbai Xu, Weiying Guo, Nanya Wang, Chaoying Liu, Pujun Gao, Jie Cao, Yang Zheng, Kaiyu Zhang, Yang Wang, Hui Chen, Jian Zhang, Dongmei Mu & Junqi Niu
Article: 2149935
Published online: 03 Jan 2023
AbstractforEffectiveness of inactivated COVID-19 vaccines against mild disease, pneumonia, and severe disease among persons infected with SARS-CoV-2 Omicron variant: real-world study in Jilin Province, China | Full Text | References | PDF (1.2 MB) | EPUB
  • 3377 Views
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Open Access

Research Article

Article
Distinct inflammation-related proteins associated with T cell immune recovery during chronic HIV-1 infection
Lin-Yu Wan, Hui-Huang Huang, Cheng Zhen, Si-Yuan Chen, Bing Song, Wen-Jing Cao, Li-Li Shen, Ming-Ju Zhou, Xiao-Chang Zhang, Ruonan Xu, Xing Fan, Ji-Yuan Zhang, Ming Shi, Chao Zhang, Yan-Mei Jiao, Jin-Wen Song & Fu-Sheng Wang
Article: 2150566
Published online: 20 Dec 2022
AbstractforDistinct inflammation-related proteins associated with T cell immune recovery during chronic HIV-1 infection | Full Text | References | PDF (2.6 MB) | EPUB
  • 2859 Views
  • 1 CrossRef citations
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Open Access
Article
Epidemiology, evolution, and biological characteristics of H6 avian influenza viruses in China
Xiaohao Xu, Qi Chen, Min Tan, Jia Liu, Xiyan Li, Lei Yang, Yuelong Shu, Dayan Wang & Wenfei Zhu
Article: 2151380
Published online: 20 Dec 2022
AbstractforEpidemiology, evolution, and biological characteristics of H6 avian influenza viruses in China | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
  • 2564 Views
  • 2 CrossRef citations
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Open Access

Coronaviruses

Article
Omicron variants escape the persistent SARS-CoV-2-specific antibody response in 2-year COVID-19 convalescents regardless of vaccination
Miao Wang, Bing Zhou, Qing Fan, Xinrong Zhou, Xuejiao Liao, Jingyan Lin, Zhenghua Ma, Jingke Dong, Haiyan Wang, Xiangyang Ge, Bin Ju & Zheng Zhang
Article: 2151381
Published online: 28 Dec 2022
AbstractforOmicron variants escape the persistent SARS-CoV-2-specific antibody response in 2-year COVID-19 convalescents regardless of vaccination | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
  • 2646 Views
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Open Access
Article
Induction of significant neutralizing antibodies against SARS-CoV-2 by a highly attenuated pangolin coronavirus variant with a 104nt deletion at the 3'-UTR
Shanshan Lu, Shengdong Luo, Chang Liu, Muli Li, Xiaoping An, Mengzhe Li, Jun Hou, Huahao Fan, Panyong Mao, Yigang Tong & Lihua Song
Article: 2151383
Published online: 18 Dec 2022
AbstractforInduction of significant neutralizing antibodies against SARS-CoV-2 by a highly attenuated pangolin coronavirus variant with a 104nt deletion at the 3'-UTR | Full Text | References | PDF (5.4 MB) | EPUB | Supplemental
  • 1901 Views
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Open Access

Research Article

Article
Complete genome sequencing and comparative genomic analyses of a new spotted-fever Rickettsia heilongjiangensis strain B8
Maozhang He, Lifeng Zhang, Haoran Hu, Xiaohan Liu, Cong Zhang, Yu Xin, Boyu Liu, Zhen Chen, Kehan Xu & Yan Liu
Article: 2153085
Published online: 13 Feb 2023
AbstractforComplete genome sequencing and comparative genomic analyses of a new spotted-fever Rickettsia heilongjiangensis strain B8 | Full Text | References | PDF (4 MB) | EPUB | Supplemental
  • 1851 Views
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Open Access

Coronaviruses

Article
A comparative analysis exposes an amplification delay distinctive to SARS-CoV-2 Omicron variants of clinical and public health relevance
K.L. Brown, A. Ceci, C. Roby, R. Briggs, D. Ziolo, R. Korba, R. Mejia, S.T. Kelly, D. Toney, M.J. Friedlander & C.V. Finkielstein
Article: 2154617
Published online: 24 Dec 2022
AbstractforA comparative analysis exposes an amplification delay distinctive to SARS-CoV-2 Omicron variants of clinical and public health relevance | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 1774 Views
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Open Access
Article
Changes in the characteristics and outcomes of COVID-19 patients from the early pandemic to the delta variant epidemic: a nationwide population-based study
Koichi Miyashita, Hironao Hozumi, Kazuki Furuhashi, Eiji Nakatani, Yusuke Inoue, Hideki Yasui, Masato Karayama, Yuzo Suzuki, Tomoyuki Fujisawa, Noriyuki Enomoto, Naoki Inui, Toshiyuki Ojima & Takafumi Suda
Article: 2155250
Published online: 20 Dec 2022
AbstractforChanges in the characteristics and outcomes of COVID-19 patients from the early pandemic to the delta variant epidemic: a nationwide population-based study | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 3336 Views
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Open Access

Research Article

Article
Identification and characterization of novel lineage 1 Powassan virus strains in New York State
Rachel E. Lange, Alan P. Dupuis II, Melissa A. Prusinski, Joseph G. Maffei, Cheri A. Koetzner, Kiet Ngo, Bryon Backenson, JoAnne Oliver, Chantal B.F. Vogels, Nathan D. Grubaugh, Laura D. Kramer & Alexander T. Ciota
Article: 2155585
Published online: 20 Dec 2022
AbstractforIdentification and characterization of novel lineage 1 Powassan virus strains in New York State | Full Text | References | PDF (1.9 MB) | EPUB
  • 1766 Views
  • 1 CrossRef citations
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Open Access
Article
A novel viral vaccine platform based on engineered transfer RNA
Tong-Yun Wang, Fan-Dan Meng, Guo-Ju Sang, Hong-Liang Zhang, Zhi-Jun Tian, Hao Zheng, Xue-Hui Cai & Yan-Dong Tang
Article: 2157339
Published online: 18 Dec 2022
AbstractforA novel viral vaccine platform based on engineered transfer RNA | Full Text | References | PDF (4.9 MB) | EPUB | Supplemental
  • 2417 Views
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Open Access
Article
Avirulent phenotype promotes Bordetella pertussis adaptation to the intramacrophage environment
Mariam R. Farman, Denisa Petráčková, Dilip Kumar, Jakub Držmíšek, Argha Saha, Ivana Čurnová, Jan Čapek, Václava Hejnarová, Fabian Amman, Ivo Hofacker & Branislav Večerek
Article: e2146536
Published online: 19 Jan 2023
AbstractforAvirulent phenotype promotes Bordetella pertussis adaptation to the intramacrophage environment | Full Text | References | PDF (3.4 MB) | EPUB | Supplemental
  • 1736 Views
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Open Access

Coronaviruses

Article
Structural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2
Mengxiao Luo, Biao Zhou, Eswar R. Reddem, Bingjie Tang, Bohao Chen, Runhong Zhou, Hang Liu, Lihong Liu, Phinikoula S. Katsamba, Ka-Kit Au, Hiu-On Man, Kelvin Kai-Wang To, Kwok-Yung Yuen, Lawrence Shapiro, Shangyu Dang, David D. Ho & Zhiwei Chen
Article: 2146538
Published online: 03 Jan 2023
AbstractforStructural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2 | Full Text | References | PDF (5.2 MB) | EPUB | Supplemental
  • 2455 Views
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Open Access

Research Article

Article
A rabies virus-vectored vaccine expressing two copies of the Marburg virus glycoprotein gene induced neutralizing antibodies against Marburg virus in humanized mice
Jinhao Bi, Haojie Wang, Qiuxue Han, Hongyan Pei, Hualei Wang, Hongli Jin, Song Jin, Hang Chi, Songtao Yang, Yongkun Zhao, Feihu Yan, Liangpeng Ge & Xianzhu Xia
Article: 2149351
Published online: 28 Dec 2022
AbstractforA rabies virus-vectored vaccine expressing two copies of the Marburg virus glycoprotein gene induced neutralizing antibodies against Marburg virus in humanized mice | Full Text | References | PDF (5.5 MB) | EPUB | Supplemental
  • 2174 Views
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Open Access

Influenza infections

Article
Influenza vaccination is associated with a reduced risk of invasive aspergillosis in high-risk individuals in Taiwan: a population-based cohort study
Yi-Jyun Chen, I-Feng Lin, Jen-Hsiang Chuang, Hung-Ling Huang & Ta-Chien Chan
Article: 2155584
Published online: 27 Dec 2022
AbstractforInfluenza vaccination is associated with a reduced risk of invasive aspergillosis in high-risk individuals in Taiwan: a population-based cohort study | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 1784 Views
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Open Access

Tuberculosis

Article
Accuracy of the InnowaveDX MTB/RIF test for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre study
Yunfeng Deng, Zichun Ma, Biyi Su, Guanghong Bai, Jianhua Pan, Quan Wang, Long Cai, Yanhua Song, Yuanyuan Shang, Pinyun Ma, Jing Li, Qianxuan Zhou, Gulibike Mulati, Dapeng Fan, Shanshan Li, Yaoju Tan & Yu Pang
Article: 2151382
Published online: 02 Jan 2023
AbstractforAccuracy of the InnowaveDX MTB/RIF test for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre study | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
  • 1986 Views
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Open Access

Coronaviruses

Article
Hybrid immunity and protection against infection during the Omicron wave in Malta
John Paul Cauchi, Ausra Dziugyte, Maria-Louise Borg, Tanya Melillo, Graziella Zahra, Christopher Barbara, Jorgen Souness, Steve Agius, Neville Calleja, Charmaine Gauci, Pauline Vassallo & Joaquin Baruch
Article: e2156814
Published online: 02 Jan 2023
AbstractforHybrid immunity and protection against infection during the Omicron wave in Malta | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 1561 Views
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Open Access

Research Article

Article
Differential effects of Usutu and West Nile viruses on neuroinflammation, immune cell recruitment and blood–brain barrier integrity
Orianne Constant, Ghizlane Maarifi, Jonathan Barthelemy, Marie-France Martin, Bachirou Tinto, Giovanni Savini, Philippe Van de Perre, Sébastien Nisole, Yannick Simonin & Sara Salinas
Article: 2156815
Published online: 02 Jan 2023
AbstractforDifferential effects of Usutu and West Nile viruses on neuroinflammation, immune cell recruitment and blood–brain barrier integrity | Full Text | References | PDF (4 MB) | EPUB | Supplemental
  • 1934 Views
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Coronaviruses

Article
Correlations of Myeloperoxidase (MPO), Adenosine deaminase (ADA), C–C motif chemokine 22 (CCL22), Tumour necrosis factor alpha (TNFα) and Interleukin-6 (IL-6) mRNA expression in the nasopharyngeal specimens with the diagnosis and severity of SARS-CoV-2 infections
Kelvin Hei-Yeung Chiu, Cyril Chik-Yan Yip, Rosana Wing-Shan Poon, Kit-Hang Leung, Xin Li, Ivan Fan-Ngai Hung, Kelvin Kai-Wang To, Vincent Chi-Chung Cheng & Kwok-Yung Yuen
Article: 2157338
Published online: 02 Jan 2023
AbstractforCorrelations of Myeloperoxidase (MPO), Adenosine deaminase (ADA), C–C motif chemokine 22 (CCL22), Tumour necrosis factor alpha (TNFα) and Interleukin-6 (IL-6) mRNA expression in the nasopharyngeal specimens with the diagnosis and severity of SARS-CoV-2 infections | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
  • 1666 Views
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Open Access

Letter

Letter
Crystal structure of vaccinia virus G3/L5 sub-complex reveals a novel fold with extended inter-molecule interactions conserved among orthopoxviruses
Sheng Lin, Dan Yue, Fanli Yang, Zimin Chen, Bin He, Yu Cao, Haohao Dong, Jian Li, Qi Zhao & Guangwen Lu
Article: e2160661
Published online: 10 Jan 2023
First Page PreviewforCrystal structure of vaccinia virus G3/L5 sub-complex reveals a novel fold with extended inter-molecule interactions conserved among orthopoxviruses | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
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Coronaviruses

Article
Cross-neutralization and viral fitness of SARS-CoV-2 Omicron sublineages
Hongjie Xia, Jason Yeung, Birte Kalveram, Cody J. Bills, John Yun-Chung Chen, Chaitanya Kurhade, Jing Zou, Steven G. Widen, Brian R. Mann, Rebecca Kondor, C. Todd Davis, Bin Zhou, David E. Wentworth, Xuping Xie & Pei-Yong Shi
Article: e2161422
Published online: 12 Jan 2023
AbstractforCross-neutralization and viral fitness of SARS-CoV-2 Omicron sublineages | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
  • 2116 Views
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Research Article

Article
Humoral and cellular immunogenicity and efficacy of a coxsackievirus A10 vaccine in mice
Huan-Huan An, Meng Li, Rui-Lun Liu, Jie Wu, Sheng-Li Meng, Jing Guo, Ze-Jun Wang, Sha-Sha Qian & Shuo Shen
Article: e2147022
Published online: 17 Jan 2023
AbstractforHumoral and cellular immunogenicity and efficacy of a coxsackievirus A10 vaccine in mice | Full Text | References | PDF (3.7 MB) | EPUB | Supplemental
  • 1338 Views
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Article
The regulation of cell homeostasis and antiviral innate immunity by autophagy during classical swine fever virus infection
Xiaowen Li, Yiwan Song, Xinyan Wang, Cheng Fu, Feifan Zhao, Linke Zou, Keke Wu, Wenxian Chen, Zhaoyao Li, Jindai Fan, Yuwan Li, Bingke Li, Sen Zeng, Xiaodi Liu, Mingqiu Zhao, Lin Yi, Jinding Chen & Shuangqi Fan
Article: 2164217
Published online: 17 Jan 2023
AbstractforThe regulation of cell homeostasis and antiviral innate immunity by autophagy during classical swine fever virus infection | Full Text | References | PDF (3.7 MB) | EPUB
  • 3168 Views
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Review

Review
Host antiviral factors hijack furin to block SARS-CoV-2, ebola virus, and HIV-1 glycoproteins cleavage
Changqing Yu, Guosheng Wang, Qiang Liu, Jingbo Zhai, Mengzhou Xue, Qiang Li, Yuanhua Xian & Chunfu Zheng
Article: 2164742
Published online: 01 Feb 2023
AbstractforHost antiviral factors hijack furin to block SARS-CoV-2, ebola virus, and HIV-1 glycoproteins cleavage | Full Text | References | PDF (2.9 MB) | EPUB
  • 2732 Views
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Coronaviruses

Article
Booster vaccination is required to elicit and maintain COVID-19 vaccine-induced immunity in SIV-infected macaques
Pingchao Li, Qian Wang, Yizi He, Chenchen Yang, Zhengyuan Zhang, Zijian Liu, Bo Liu, Li Yin, Yilan Cui, Peiyu Hu, Yichu Liu, Pingqian Zheng, Wei Wang, Linbing Qu, Caijun Sun, Suhua Guan, Liqiang Feng & Ling Chen
Article: e2136538
Published online: 01 Mar 2023
AbstractforBooster vaccination is required to elicit and maintain COVID-19 vaccine-induced immunity in SIV-infected macaques | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 1890 Views
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Ebola

Article
In vivo characterization of the novel ebolavirus Bombali virus suggests a low pathogenic potential for humans
B. S. Bodmer, A. Breithaupt, M. Heung, J. E. Brunetti, C. Henkel, J. Müller-Guhl, E. Rodríguez, L. Wendt, S. L. Winter, M. Vallbracht, A. Müller, S. Römer, P. Chlanda, C. Muñoz-Fontela, T. Hoenen & B. Escudero-Pérez
Article: 2164216
Published online: 18 Jan 2023
AbstractforIn vivo characterization of the novel ebolavirus Bombali virus suggests a low pathogenic potential for humans | Full Text | References | PDF (3.6 MB) | EPUB | Supplemental
  • 2362 Views
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Influenza infections

Article
Influenza viral infection is a risk factor for severe illness in COVID-19 patients: a nationwide population-based cohort study
Jeong-Hwan Hwang, Yeon Seok You, Sang Woo Yeom, Min Gyu Lee, Jong-hwan Lee, Min Gul Kim & Jong Seung Kim
Article: 2164215
Published online: 19 Jan 2023
AbstractforInfluenza viral infection is a risk factor for severe illness in COVID-19 patients: a nationwide population-based cohort study | Full Text | References | PDF (1.6 MB) | EPUB
  • 2261 Views
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Coronaviruses

Review
The nasopharyngeal microbiome in COVID-19
Sergio Candel, Sylwia D. Tyrkalska, Carmen Álvarez-Santacruz & Victoriano Mulero
Article: e2165970
Published online: 20 Jan 2023
AbstractforThe nasopharyngeal microbiome in COVID-19 | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 2315 Views
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Antimicrobial Agents

Article
Phylogenetic analysis and virulence characteristics of methicillin-resistant Staphylococcus aureus ST764-SCCmec II: an emerging hypervirulent clone ST764-t1084 in China
Yanghua Xiao, Weihua Han, Bingjie Wang, Yanlei Xu, Huilin Zhao, Xinyi Wang, Lulin Rao, Jiao Zhang, Li Shen, Hui Zhou, Long Hu, Junhong Shi, Jingyi Yu, Yinjuan Guo, Han Xia & Fangyou Yu
Article: 2165969
Published online: 20 Jan 2023
AbstractforPhylogenetic analysis and virulence characteristics of methicillin-resistant Staphylococcus aureus ST764-SCCmec II: an emerging hypervirulent clone ST764-t1084 in China | Full Text | References | PDF (4 MB) | EPUB | Supplemental
  • 2235 Views
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Coronaviruses

Review
The role of SARS-CoV-2 nucleocapsid protein in antiviral immunity and vaccine development
Haiyun Yu, Fei Guan, Heather Miller, Jiahui Lei & Chaohong Liu
Article: e2164219
Published online: 01 Mar 2023
AbstractforThe role of SARS-CoV-2 nucleocapsid protein in antiviral immunity and vaccine development | Full Text | References | PDF (1.6 MB) | EPUB
  • 2670 Views
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Article
Genetic diversity and molecular epidemiology of Middle East Respiratory Syndrome Coronavirus in dromedaries in Ethiopia, 2017–2020
Ziqi Zhou, Abraham Ali, Elias Walelign, Getnet F. Demissie, Ihab El Masry, Takele Abayneh, Belayneh Getachew, Pavithra Krishnan, Daisy Y.M. Ng, Emma Gardner, Yilma Makonnen, Eve Miguel, Véronique Chevalier, Daniel K. Chu, Ray T. Y. So, Sophie Von Dobschuetz, Gezahegne Mamo, Leo L. M. Poon & Malik Peiris
Article: e2164218
Published online: 27 Jan 2023
AbstractforGenetic diversity and molecular epidemiology of Middle East Respiratory Syndrome Coronavirus in dromedaries in Ethiopia, 2017–2020 | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
  • 2452 Views
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Article
Vaccination effects on post-infection outcomes in the Omicron BA.2 outbreak in Shanghai
Qianhui Wu, Hongyu Wang, Jianpeng Cai, Jingwen Ai, Yang Li, Haocheng Zhang, Sen Wang, Feng Sun, Yanpeng Wu, Jiaxin Zhou, Yan Wang, Hongjie Yu & Wenhong Zhang
Article: e2169197
Published online: 27 Jan 2023
AbstractforVaccination effects on post-infection outcomes in the Omicron BA.2 outbreak in Shanghai | Full Text | References | PDF (916.2 KB) | EPUB
  • 2084 Views
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Tuberculosis

Article
Tuberculosis preventive treatment among individuals with inactive tuberculosis suggested by untreated radiographic abnormalities: a community-based randomized controlled trial
Haoran Zhang, Henan Xin, Ying Du, Xuefang Cao, Shouguo Pan, Jianmin Liu, Ling Guan, Fei Shen, Zisen Liu, Bin Zhang, Dakuan Wang, Boxuan Feng, Jiang Du, Xueling Guan, Yijun He, Yongpeng He, Zhanjiang Zhang, Jiaoxia Yan, Qi Jin, Lei Gao & for the LATENTTB TRIAL2-NSTM study team
Article: e2169195
Published online: 27 Jan 2023
AbstractforTuberculosis preventive treatment among individuals with inactive tuberculosis suggested by untreated radiographic abnormalities: a community-based randomized controlled trial | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 1829 Views
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Research Article

Article
Risk assessment of the newly emerged H7N9 avian influenza viruses
Pengxiang Chang, Jean-Remy Sadeyen, Sushant Bhat, Rebecca Daines, Altaf Hussain, Huseyin Yilmaz & Munir Iqbal
Article: 2172965
Published online: 08 Feb 2023
AbstractforRisk assessment of the newly emerged H7N9 avian influenza viruses | Full Text | References | PDF (1.8 MB) | EPUB
  • 2124 Views
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Coronaviruses

Article
Coronavirus RNA-dependent RNA polymerase interacts with the p50 regulatory subunit of host DNA polymerase delta and plays a synergistic role with RNA helicase in the induction of DNA damage response and cell cycle arrest in the S phase
Li Quan, Xinxin Sun, Linghui Xu, Rui Ai Chen & Ding Xiang Liu
Article: e2176008
Published online: 15 Feb 2023
AbstractforCoronavirus RNA-dependent RNA polymerase interacts with the p50 regulatory subunit of host DNA polymerase delta and plays a synergistic role with RNA helicase in the induction of DNA damage response and cell cycle arrest in the S phase | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
  • 1545 Views
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Article
Real-life effectiveness of COVID-19 vaccine during the Omicron variant-dominant pandemic: how many booster doses do we need?
Paskorn Sritipsukho, Thana Khawcharoenporn, Boonying Siribumrungwong, Pansachee Damronglerd, Nuntra Suwantarat, Araya Satdhabudha, Chanapai Chaiyakulsil, Phakatip Sinlapamongkolkul, Auchara Tangsathapornpong, Pornumpa Bunjoungmanee, Sira Nanthapisal, Chamnan Tanprasertkul, Naiyana Sritipsukho, Chatchai Mingmalairak, Anucha Apisarnthanarak & Pichaya Tantiyavarong
Article: 2174779
Published online: 15 Feb 2023
AbstractforReal-life effectiveness of COVID-19 vaccine during the Omicron variant-dominant pandemic: how many booster doses do we need? | Full Text | References | PDF (1,015.9 KB) | EPUB | Supplemental
  • 1697 Views
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Research Article

Article
A mouse model and pathogenesis study for CVA19 first isolated from hand, foot, and mouth disease
Wangquan Ji, Ling Tao, Dong Li, Peiyu Zhu, Yuexia Wang, Yu Zhang, Liang Zhang, Shuaiyin Chen, Haiyan Yang, Yuefei Jin & Guangcai Duan
Article: 2177084
Published online: 15 Feb 2023
AbstractforA mouse model and pathogenesis study for CVA19 first isolated from hand, foot, and mouth disease | Full Text | References | PDF (6.2 MB) | EPUB
  • 1398 Views
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Article
Cervical HPV infection in Guangzhou, China: an epidemiological study of 198,111 women from 2015 to 2021
Xiaohan Yang, Yuanyuan Li, Yuan Tang, Zhiyu Li, Sanfeng Wang, Xiping Luo, Tianwen He, Aihua Yin & Mingyong Luo
Article: e2176009
Published online: 15 Feb 2023
AbstractforCervical HPV infection in Guangzhou, China: an epidemiological study of 198,111 women from 2015 to 2021 | Full Text | References | PDF (2.7 MB) | EPUB | Supplemental
  • 2030 Views
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Article
Antibody avidity to pertussis toxin after acellular pertussis vaccination and infection
Aapo Knuutila, Tine Dalby, Niina Ahvenainen, Alex-Mikael Barkoff, Charlotte Sværke Jørgensen, Kurt Fuursted, Jussi Mertsola & Qiushui He
Article: e2174782
Published online: 16 Feb 2023
AbstractforAntibody avidity to pertussis toxin after acellular pertussis vaccination and infection | Full Text | References | PDF (1.3 MB) | EPUB
  • 1122 Views
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Coronaviruses

Article
SARS-CoV-2 infection-induced immunity reduces rates of reinfection and hospitalization caused by the Delta or Omicron variants
Marc-Antoine de La Vega, Efstathia Polychronopoulou, Ara XIII, Zhe Ding, Tong Chen, Qixing Liu, Jiaming Lan, Marie-Edith Nepveu-Traversy, Hugues Fausther-Bovendo, Mohammed F. Zaidan, Gary Wong, Gulshan Sharma & Gary P. Kobinger
Article: e2169198
Published online: 01 Mar 2023
AbstractforSARS-CoV-2 infection-induced immunity reduces rates of reinfection and hospitalization caused by the Delta or Omicron variants | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 1765 Views
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Hepatitis

Article
CRISPR/Cas13a-assisted rapid and portable HBV DNA detection for low-level viremia patients
Yuan Tian, Zihao Fan, Ling Xu, Yaling Cao, Sisi Chen, Zhenzhen Pan, Yao Gao, Hao Li, Sujun Zheng, Yingmin Ma, Zhongping Duan, Xiangying Zhang & Feng Ren
Article: e2177088
Published online: 20 Feb 2023
AbstractforCRISPR/Cas13a-assisted rapid and portable HBV DNA detection for low-level viremia patients | Full Text | References | PDF (2.7 MB) | EPUB | Supplemental
  • 2762 Views
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Zika

Article
Identification of novel anti-ZIKV drugs from viral-infection temporal gene expression profiles
Nailou Zhang, Zhongyuan Tan, Jinbo Wei, Sai Zhang, Yan Liu, Yuanjiu Miao, Qingwen Ding, Wenfu Yi, Min Gan, Chunjie Li, Bin Liu, Hanzhong Wang & Zhenhua Zheng
Article: 2174777
Published online: 20 Feb 2023
AbstractforIdentification of novel anti-ZIKV drugs from viral-infection temporal gene expression profiles | Full Text | References | PDF (3.8 MB) | EPUB
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Research Article

Article
NSUN2-mediated m5C methylation of IRF3 mRNA negatively regulates type I interferon responses during various viral infections
Hongyun Wang, Jiangpeng Feng, Cong Zeng, Jiejie Liu, Zhiying Fu, Dehe Wang, Yafen Wang, Lu Zhang, Jiali Li, Ao Jiang, Miao He, Yuanyuan Cao, Kun Yan, Hao Tang, Deyin Guo, Ke Xu, Xiang Zhou, Li Zhou, Ke Lan, Yu Zhou & Yu Chen
Article: 2178238
Published online: 20 Feb 2023
AbstractforNSUN2-mediated m5C methylation of IRF3 mRNA negatively regulates type I interferon responses during various viral infections | Full Text | References | PDF (4.8 MB) | EPUB | Supplemental
  • 3317 Views
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Coronaviruses

Letter
A booster of Delta-Omicron RBD-dimer protein subunit vaccine augments sera neutralization of Omicron sub-variants BA.1/BA.2/BA.2.12.1/BA.4/BA.5
Minrun Duan, Huixin Duan, Yaling An, Tianyi Zheng, Shengfeng Wan, Hui Wang, Xin Zhao, Lianpan Dai, Kun Xu & George F. Gao
Article: e2179357
Published online: 27 Feb 2023
AbstractforA booster of Delta-Omicron RBD-dimer protein subunit vaccine augments sera neutralization of Omicron sub-variants BA.1/BA.2/BA.2.12.1/BA.4/BA.5 | Full Text | References | PDF (996.6 KB) | EPUB | Supplemental
  • 1595 Views
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Review

Review
Development of animal models for emerging infectious diseases by breaking the barrier of species susceptibility to human pathogens
Na Rong & Jiangning Liu
Article: 2178242
Published online: 23 Feb 2023
AbstractforDevelopment of animal models for emerging infectious diseases by breaking the barrier of species susceptibility to human pathogens | Full Text | References | PDF (1.3 MB) | EPUB
  • 1226 Views
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Coronaviruses

Article
SARS-CoV-2 Omicron subvariants exhibit distinct fusogenicity, but similar sensitivity, to pan-CoV fusion inhibitors
Shuai Xia, Lijue Wang, Fanke Jiao, Xueying Yu, Wei Xu, Ziqi Huang, Xicheng Li, Qian Wang, Yun Zhu, Qiuhong Man, Shibo Jiang & Lu Lu
Article: 2178241
Published online: 23 Feb 2023
AbstractforSARS-CoV-2 Omicron subvariants exhibit distinct fusogenicity, but similar sensitivity, to pan-CoV fusion inhibitors | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
  • 1798 Views
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Research Article

Article
Risk factors for Borna disease virus 1 encephalitis in Germany – a case–control study
Kirsten Pörtner, Hendrik Wilking, Christina Frank, Merle M. Böhmer, Klaus Stark & Dennis Tappe
Article: e2174778
Published online: 27 Feb 2023
AbstractforRisk factors for Borna disease virus 1 encephalitis in Germany – a case–control study | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
  • 3390 Views
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Article
Substitution of gp120 C4 region compensates for V3 loss-of-fitness mutations in HIV-1 CRF01_AE co-receptor switching
Yueyang Yu, Yi Feng, Zehua Zhou, Kang Li, Xiaoyan Hu, Lingjie Liao, Hui Xing & Yimig Shao
Article: e2169196
Published online: 28 Feb 2023
AbstractforSubstitution of gp120 C4 region compensates for V3 loss-of-fitness mutations in HIV-1 CRF01_AE co-receptor switching | Full Text | References | PDF (2.2 MB) | EPUB
  • 1127 Views
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Tuberculosis

Review
Designing molecular diagnostics for current tuberculosis drug regimens
Sophia B. Georghiou, Margaretha de Vos, Kavindhran Velen, Paolo Miotto, Rebecca E. Colman, Daniela Maria Cirillo, Nazir Ismail, Timothy C. Rodwell, Anita Suresh & Morten Ruhwald
Article: 2178243
Published online: 27 Feb 2023
AbstractforDesigning molecular diagnostics for current tuberculosis drug regimens | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
  • 2660 Views
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Research Article

Article
Magnetic resonance imaging of human variegated squirrel bornavirus 1 (VSBV-1) encephalitis reveals diagnostic pattern indistinguishable from Borna disease virus 1 (BoDV-1) encephalitis but typical for bornaviruses
Monika Huhndorf, Julia Juhasz, Mike P. Wattjes, Andreas Schilling, Stefan Schob, Ingmar Kaden, Günter Klaß & Dennis Tappe
Article: 2179348
Published online: 27 Feb 2023
AbstractforMagnetic resonance imaging of human variegated squirrel bornavirus 1 (VSBV-1) encephalitis reveals diagnostic pattern indistinguishable from Borna disease virus 1 (BoDV-1) encephalitis but typical for bornaviruses | Full Text | References | PDF (1.4 MB) | EPUB
  • 1214 Views
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Influenza infections

Letter
Highly pathogenic avian influenza H5N1 virus outbreak among Cape cormorants (Phalacrocorax capensis) in Namibia, 2022
Umberto Molini, John Yabe, Irene K. Meki, Hatem Ouled Ahmed Ben Ali, Tirumala B. K. Settypalli, Sneha Datta, Lauren Michelle Coetzee, Ellini Hamunyela, Siegfried Khaiseb, Giovanni Cattoli, Charles E. Lamien & William G. Dundon
Article: 2167610
Published online: 01 Mar 2023
AbstractforHighly pathogenic avian influenza H5N1 virus outbreak among Cape cormorants (Phalacrocorax capensis) in Namibia, 2022 | Full Text | References | PDF (1.7 MB) | EPUB
  • 1737 Views
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Letter

Letter
Structural basis of poxvirus A16/G9 binding for sub-complex formation
Fanli Yang, Sheng Lin, Zimin Chen, Dan Yue, Ming Yang, Bin He, Yu Cao, Haohao Dong, Jian Li, Qi Zhao & Guangwen Lu
Article: 2179351
Published online: 01 Mar 2023
First Page PreviewforStructural basis of poxvirus A16/G9 binding for sub-complex formation | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
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Antimicrobial Agents

Article
Directed carbapenemase testing is no longer just for Enterobacterales: cost, labor, and workflow assessment of expanding carbapenemase testing to carbapenem-resistant P. aeruginosa
Christian M. Gill, Poonam Rajkotia, Amity L. Roberts, Fred C. Tenover & David P. Nicolau
Article: 2179344
Published online: 01 Mar 2023
AbstractforDirected carbapenemase testing is no longer just for Enterobacterales: cost, labor, and workflow assessment of expanding carbapenemase testing to carbapenem-resistant P. aeruginosa | Full Text | References | PDF (1.3 MB) | EPUB
  • 1420 Views
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Influenza infections

Letter
Emerging triple-reassortant influenza C virus with household-associated infection during an influenza A(H3N2) outbreak, China, 2022
Lan Cao, Ying Lu, Chaojun Xie, Yiyun Chen, Lijun Liang, Tengfei Zhou, Ziyi Zeng, Chen Wen, Biao Di, Baisheng Li, Kuibiao Li & Zhoubin Zhang
Article: 2175593
Published online: 07 Mar 2023
AbstractforEmerging triple-reassortant influenza C virus with household-associated infection during an influenza A(H3N2) outbreak, China, 2022 | Full Text | References | PDF (1.9 MB) | EPUB
  • 1149 Views
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Open Access
Article
Prevalence, evolution, replication and transmission of H3N8 avian influenza viruses isolated from migratory birds in eastern China from 2017 to 2021
Yanwen Wang, Mengjing Wang, Hong Zhang, Conghui Zhao, Yaping Zhang, Jinyan Shen, Xiaohong Sun, Hongke Xu, Yujiao Xie, Xinxin Gao, Pengfei Cui, Dong Chu, Yubao Li, Wenqiang Liu, Peng Peng, Guohua Deng, Jing Guo & Xuyong Li
Article: 2184178
Published online: 13 Mar 2023
AbstractforPrevalence, evolution, replication and transmission of H3N8 avian influenza viruses isolated from migratory birds in eastern China from 2017 to 2021 | Full Text | References | PDF (5.1 MB) | EPUB | Supplemental
  • 2220 Views
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Coronaviruses

Letter
Increase over time of antibody levels 3 months after a booster dose as an indication of better protection against Omicron infection
Rea Bingula, Hélène Chabrolles, Benjamin Bonnet, Christine Archimbaud, Amélie Brebion, Justine Cosme, Amandine Ollier, Frédéric Dutheil, Maud Junda, Audrey Mirand, Christel Regagnon, Magali Vidal, Cécile Henquell & Bertrand Evrard
Article: 2184176
Published online: 09 Mar 2023
AbstractforIncrease over time of antibody levels 3 months after a booster dose as an indication of better protection against Omicron infection | Full Text | References | PDF (878.3 KB) | EPUB | Supplemental
  • 1139 Views
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Review

Review
Follow-up outcomes of asymptomatic brucellosis: a systematic review and meta-analysis
Fande Li, Lanping Du, Hua Zhen, Mujinyan Li, Shuqi An, Wenqi Fan, Yuke Yan, Meifang Zhao, Xin Han, Zhuo Li, Huixin Yang, Cui Zhang, Chao Guo & Qing Zhen
Article: 2185464
Published online: 13 Mar 2023
AbstractforFollow-up outcomes of asymptomatic brucellosis: a systematic review and meta-analysis | Full Text | References | PDF (1.6 MB) | EPUB | Supplemental
  • 1270 Views
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Coronaviruses

Article
HLA-Bw4 in association with KIR3DL1 favors natural killer cell-mediated protection against severe COVID-19
Ruihua Wang, Ying Sun, Bo-Hua Kuang, Xiao Yan, Jinju Lei, Yu-Xin Lin, Jinxiu Tian, Yating Li, Xiaoduo Xie, Tao Chen, Hui Zhang, Yi-Xin Zeng, Jincun Zhao & Lin Feng
Article: 2185467
Published online: 13 Mar 2023
AbstractforHLA-Bw4 in association with KIR3DL1 favors natural killer cell-mediated protection against severe COVID-19 | Full Text | References | PDF (5 MB) | EPUB | Supplemental
  • 1775 Views
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Research Article

Article
Cross-species infection potential of avian influenza H13 viruses isolated from wild aquatic birds to poultry and mammals
Weiyang Sun, Menglin Zhao, Zhijun Yu, Yuanguo Li, Xinghai Zhang, Na Feng, Tiecheng Wang, Hongmei Wang, Hongbin He, Yongkun Zhao, Songtao Yang, Xianzhu Xia & Yuwei Gao
Article: e2184177
Published online: 13 Mar 2023
AbstractforCross-species infection potential of avian influenza H13 viruses isolated from wild aquatic birds to poultry and mammals | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
  • 1420 Views
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Influenza infections

Article
Characterization of neurotropic HPAI H5N1 viruses with novel genome constellations and mammalian adaptive mutations in free-living mesocarnivores in Canada
Tamiru N. Alkie, Sherri Cox, Carissa Embury-Hyatt, Brian Stevens, Neil Pople, Margo J. Pybus, Wanhong Xu, Tamiko Hisanaga, Matthew Suderman, Janice Koziuk, Peter Kruczkiewicz, Hoang Hai Nguyen, Mathew Fisher, Oliver Lung, Cassidy N. G. Erdelyan, Orie Hochman, Davor Ojkic, Carmencita Yason, Maria Bravo-Araya, Laura Bourque, Trent K. Bollinger, Catherine Soos, Jolene Giacinti, Jennifer Provencher, Sarah Ogilvie, Amanda Clark, Robyn MacPhee, Glen J. Parsons, Hazel Eaglesome, Sayrah Gilbert, Kelsey Saboraki, Richard Davis, Alexandra Jerao, Matthew Ginn, Megan E.B. Jones & Yohannes Berhane
Article: 2186608
Published online: 15 Mar 2023
AbstractforCharacterization of neurotropic HPAI H5N1 viruses with novel genome constellations and mammalian adaptive mutations in free-living mesocarnivores in Canada | Full Text | References | PDF (3.9 MB) | EPUB | Supplemental
  • 5661 Views
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Hepatitis

Article
Safety of hepatitis E vaccination for pregnancy: a post-hoc analysis of a randomized, double-blind, controlled phase 3 clinical trial
Guohua Zhong, Chunlan Zhuang, Xiaowen Hu, Qi Chen, Zhaofeng Bi, Xinhua Jia, Siying Peng, Yufei Li, Yue Huang, Qiufen Zhang, Ying Hong, Youlin Qiao, Yingying Su, Huirong Pan, Ting Wu, Lihui Wei, Shoujie Huang, Jun Zhang & Ningshao Xia
Article: 2185456
Published online: 15 Mar 2023
AbstractforSafety of hepatitis E vaccination for pregnancy: a post-hoc analysis of a randomized, double-blind, controlled phase 3 clinical trial | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 2065 Views
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Coronaviruses

Article
Effectiveness of BNT162b2 and CoronaVac vaccines in preventing SARS-CoV-2 Omicron infections, hospitalizations, and severe complications in the pediatric population in Hong Kong: a case-control study
Vincent Ka Chun Yan, Franco Wing Tak Cheng, Celine Sze Ling Chui, Francisco Tsz Tsun Lai, Carlos King Ho Wong, Xue Li, Eric Yuk Fai Wan, Joshua Sung Chih Wong, Esther Wai Yin Chan, Ian Chi Kei Wong, Mike Yat Wah Kwan & Patrick Ip
Article: 2185455
Published online: 15 Mar 2023
AbstractforEffectiveness of BNT162b2 and CoronaVac vaccines in preventing SARS-CoV-2 Omicron infections, hospitalizations, and severe complications in the pediatric population in Hong Kong: a case-control study | Full Text | References | PDF (3.2 MB) | EPUB | Supplemental
  • 2419 Views
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Tuberculosis

Article
Efficacy and safety of an innovative short-course regimen containing clofazimine for treatment of drug-susceptible tuberculosis: a clinical trial
Xubin Zheng, Xuwei Gui, Lan Yao, Jun Ma, Yifan He, Hai Lou, Jin Gu, Ruoyan Ying, Liping Chen, Qin Sun, Yidian Liu, Chih-Ming Ho, Bai-Yu Lee, Daniel L. Clemens, Marcus A. Horwitz, Xianting Ding, Xiaohui Hao, Hua Yang & Wei Sha
Article: 2187247
Published online: 17 Mar 2023
AbstractforEfficacy and safety of an innovative short-course regimen containing clofazimine for treatment of drug-susceptible tuberculosis: a clinical trial | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 1425 Views
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Coronaviruses

Article Commentary
Impact of National Omicron Outbreak at the end of 2022 on the future outlook of COVID-19 in China
Liwei Zheng, Shuying Liu & Fengmin Lu
Article: 2191738
Published online: 27 Mar 2023
First Page PreviewforImpact of National Omicron Outbreak at the end of 2022 on the future outlook of COVID-19 in China | Full Text | References | PDF (878.1 KB) | EPUB
  • 1825 Views
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Research Article

Article
Phylogenetic landscape of Monkeypox Virus (MPV) during the early outbreak in New York City, 2022
Luz H. Patiño, Susana Guerra, Marina Muñoz, Nicolas Luna, Keith Farrugia, Adriana van de Guchte, Zain Khalil, Ana Silvia Gonzalez-Reiche, Matthew M. Hernandez, Radhika Banu, Paras Shrestha, Bernadette Liggayu, Adolfo Firpo Betancourt, David Reich, Carlos Cordon-Cardo, Randy Albrecht, Rebecca Pearl, Viviana Simon, Aria Rooker, Emilia Mia Sordillo, Harm van Bakel, Adolfo García-Sastre, Dusan Bogunovic, Gustavo Palacios, Alberto Paniz Mondolfi & Juan David Ramírez
Article: e2192830
Published online: 17 Apr 2023
AbstractforPhylogenetic landscape of Monkeypox Virus (MPV) during the early outbreak in New York City, 2022 | Full Text | References | PDF (2 MB) | EPUB | Supplemental
  • 1721 Views
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Coronaviruses

Article Commentary
Application of “B+1” heterologous boosting strategy for preventing infection of SARS-CoV-2 variants with resistance to broad-spectrum coronavirus vaccines
Zezhong Liu, Lu Lu & Shibo Jiang
Article: 2192817
Published online: 03 Apr 2023
First Page PreviewforApplication of “B+1” heterologous boosting strategy for preventing infection of SARS-CoV-2 variants with resistance to broad-spectrum coronavirus vaccines | Full Text | References | PDF (622 KB) | EPUB
  • 858 Views
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Tuberculosis

Article
Discrepancy in the transmissibility of multidrug-resistant mycobacterium tuberculosis in urban and rural areas in China
Meng Li, Liping Lu, Mingcheng Guo, Qi Jiang, Lan Xia, Yuan Jiang, Shu Zhang, Yong Qiu, Chongguang Yang, Yiwang Chen, Jianjun Hong, Xiaoqin Guo, Howard Takiff, Xin Shen, Chuang Chen & Qian Gao
Article: 2192301
Published online: 29 Mar 2023
AbstractforDiscrepancy in the transmissibility of multidrug-resistant mycobacterium tuberculosis in urban and rural areas in China | Full Text | References | PDF (1.6 MB) | EPUB | Supplemental
  • 1422 Views
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Research Article

Article
Inhalable vaccine of bacterial culture supernatant extract mediates protection against fatal pulmonary anthrax
Li-Na Zhai, Yue Zhao, Xiao-Lin Song, Tong-Tong Qin, Zhi-Jun Zhang, Jia-Zhen Wang, Cheng-Yu Sui, Li-Li Zhang, Meng Lv, Ling-Fei Hu, Dong-Sheng Zhou, Tong-Yu Fang, Wen-Hui Yang & Yan-Chun Wang
Article: 2191741
Published online: 31 Mar 2023
AbstractforInhalable vaccine of bacterial culture supernatant extract mediates protection against fatal pulmonary anthrax | Full Text | References | PDF (3.7 MB) | EPUB | Supplemental
  • 1441 Views
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Non-Neutralizing Protective Antibodies

Article
Bivalent vaccines effectively protect mice against influenza A and respiratory syncytial viruses
Sathya N. Thulasi Raman, Adrian Zetner, Anwar M. Hashem, Devina Patel, Jianguo Wu, Caroline Gravel, Jun Gao, Wanyue Zhang, Annabelle Pfeifle, Levi Tamming, Karan Parikh, Jingxin Cao, Roger Tam, David Safronetz, Wangxue Chen, Michael J.W. Johnston, Lisheng Wang, Simon Sauve, Michael Rosu-Myles, Gary Van Domselaar & Xuguang Li
Article: 2192821
Published online: 09 May 2023
AbstractforBivalent vaccines effectively protect mice against influenza A and respiratory syncytial viruses | Full Text | References | PDF (2.7 MB) | EPUB | Supplemental
  • 1283 Views
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Antimicrobial Agents

Article
Evaluation of acellular pertussis vaccine: comparisons among different strains of mice
Jie Wei, Jiaona Guang, Chen Wei, Hong Wang, Jiaqi Zhou, Huan Li, Lichan Wang, Xiao Ma & Bingfei Yue
Article: e2192822
Published online: 31 Mar 2023
AbstractforEvaluation of acellular pertussis vaccine: comparisons among different strains of mice | Full Text | References | PDF (1.3 MB) | EPUB
  • 959 Views
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Enterovirus 71 (EV71)

Article
Integrated analysis reveals important differences in the gut and oropharyngeal microbiota between children with mild and severe hand, foot, and mouth disease
Nan Zhang, Danlei Mou, Tongzeng Li, Zhiyun Chen, Chunhua Ma, Lianchun Liang & Qiushui He
Article: 2192819
Published online: 31 Mar 2023
AbstractforIntegrated analysis reveals important differences in the gut and oropharyngeal microbiota between children with mild and severe hand, foot, and mouth disease | Full Text | References | PDF (2.9 MB) | EPUB | Supplemental
  • 1134 Views
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Research Article

Article
Rational development of multicomponent mRNA vaccine candidates against mpox
Rong-Rong Zhang, Zheng-Jian Wang, Yi-Long Zhu, Wei Tang, Chao Zhou, Suo-Qun Zhao, Mei Wu, Tao Ming, Yong-Qiang Deng, Qi Chen, Ning-Yi Jin, Qing Ye, Xiao Li & Cheng-Feng Qin
Article: 2192815
Published online: 31 Mar 2023
AbstractforRational development of multicomponent mRNA vaccine candidates against mpox | Full Text | References | PDF (2.7 MB) | EPUB | Supplemental
  • 2928 Views
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Coronaviruses

Article
Characterizing the cellular and molecular variabilities of peripheral immune cells in healthy recipients of BBIBP-CorV inactivated SARS-CoV-2 vaccine by single-cell RNA sequencing
Renyang Tong, Lingjie Luo, Yichao Zhao, Mingze Sun, Ronghong Li, Jianmei Zhong, Yifan Chen, Liuhua Hu, Zheng Li, Jianfeng Shi, Yuyan Lyu, Li Hu, Xiao Guo, Qi Liu, Tian Shuang, Chenjie Zhang, Ancai Yuan, Lingyue Sun, Zheng Zhang, Kun Qian, Lei Chen, Wei Lin, Alex F. Chen, Feng Wang & Jun Pu
Article: e2187245
Published online: 09 May 2023
AbstractforCharacterizing the cellular and molecular variabilities of peripheral immune cells in healthy recipients of BBIBP-CorV inactivated SARS-CoV-2 vaccine by single-cell RNA sequencing | Full Text | References | PDF (4.9 MB) | EPUB | Supplemental
  • 1923 Views
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Research Article

Article
Emergence of an ancient and pathogenic mammarenavirus
Xue-Lian Luo, Shan Lu, Chuan Qin, Mang Shi, Xiao-Bo Lu, Lu Wang, Sang Ga, Dong Jin, Xin-Li Ma, Jing Yang, Yan Dai, Lin-Lin Bao, Yan-Peng Cheng, Ya-Jun Ge, Yi-Bo Bai, Wen-Tao Zhu, Ji Pu, Hui Sun, Yu-Yuan Huang, Ming-Chao Xu, Wen-Jing Lei, Kui Dong, Cai-Xin Yang, Yi-Fan Jiao, Qi Lv, Feng-Di Li & Jianguo Xu
Article: e2192816
Published online: 11 Apr 2023
AbstractforEmergence of an ancient and pathogenic mammarenavirus | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 2053 Views
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Coronaviruses

Article
Berbamine suppresses intestinal SARS-CoV-2 infection via a BNIP3-dependent autophagy blockade
Alexandra P. M. Cloherty, Anusca G. Rader, Kharishma S. Patel, Jimena Pérez-Vargas, Connor A. H. Thompson, Siobhan Ennis, Masahiro Niikura, Manon E. Wildenberg, Vanesa Muncan, Renée R. C. E. Schreurs, François Jean & Carla M. S. Ribeiro
Article: 2195020
Published online: 17 Apr 2023
AbstractforBerbamine suppresses intestinal SARS-CoV-2 infection via a BNIP3-dependent autophagy blockade | Full Text | References | PDF (3.5 MB) | EPUB | Supplemental
  • 2027 Views
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Review
The role of dendritic cells in COVID-19 infection
Xuying Wang, Fei Guan, Heather Miller, Maria G Byazrova, Fabio Candotti, Kamel Benlagha, Niels Olsen Saraiva Camara, Jiahui Lei, Alexander Filatov & Chaohong Liu
Article: 2195019
Published online: 09 May 2023
AbstractforThe role of dendritic cells in COVID-19 infection | Full Text | References | PDF (1.1 MB) | EPUB
  • 1390 Views
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Non-Neutralizing Protective Antibodies

Article
Omicron BA.1 breakthrough infections in inactivated COVID-19 vaccine recipients induced distinct pattern of antibody and T cell responses to different Omicron sublineages
Li Guo, Qiao Zhang, Jingchuan Zhong, Lan Chen, Wentao Jiang, Tingxuan Huang, Yanan Li, Yin Zhang, Liuhui Xu, Xinming Wang, Yan Xiao, Ying Wang, Xiaojing Dong, Tao Dong, Yanchun Peng, Biao Zhang, Yan Xie, Hongmei Gao, Zhongyang Shen, Lili Ren, Tao Cheng & Jianwei Wang
Article: 2202263
Published online: 01 May 2023
AbstractforOmicron BA.1 breakthrough infections in inactivated COVID-19 vaccine recipients induced distinct pattern of antibody and T cell responses to different Omicron sublineages | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 1950 Views
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Coronaviruses

Article
Potent immunogenicity and broad-spectrum protection potential of microneedle array patch-based COVID-19 DNA vaccine candidates encoding dimeric RBD chimera of SARS-CoV and SARS-CoV-2 variants
Feng Fan, Xin Zhang, Zhiyu Zhang, Yuan Ding, Limei Wang, Xin Xu, Yaying Pan, Fang-Yuan Gong, Lin Jiang, Lingyu Kang, Zhuo Ha, Huijun Lu, Jiawang Hou, Zhihua Kou, Gan Zhao, Bin Wang & Xiao-Ming Gao
Article: 2202269
Published online: 01 May 2023
AbstractforPotent immunogenicity and broad-spectrum protection potential of microneedle array patch-based COVID-19 DNA vaccine candidates encoding dimeric RBD chimera of SARS-CoV and SARS-CoV-2 variants | Full Text | References | PDF (3.6 MB) | EPUB | Supplemental
  • 1639 Views
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Article
Reinfection rate and disease severity of the BA.5 Omicron SARS-CoV-2 lineage compared to previously circulating variants of concern in the Canary Islands (Spain)
Laura Ciuffreda, José M. Lorenzo-Salazar, Diego García-Martínez de Artola, Helena Gil-Campesino, Julia Alcoba-Florez, Héctor Rodríguez-Pérez, Antonio Íñigo-Campos, Josmar Salas-Hernández, Julia Rodríguez-Nuñez, Adrián Muñoz-Barrera, Agustín Valenzuela-Fernández, Oscar Díez-Gil, Rafaela González-Montelongo & Carlos Flores
Article: 2202281
Published online: 01 May 2023
AbstractforReinfection rate and disease severity of the BA.5 Omicron SARS-CoV-2 lineage compared to previously circulating variants of concern in the Canary Islands (Spain) | Full Text | References | PDF (1.6 MB) | EPUB | Supplemental
  • 996 Views
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Influenza infections

Article
Development of an mRNA vaccine against a panel of heterologous H1N1 seasonal influenza viruses using a consensus hemagglutinin sequence
Ning Ma, Zhi-Wu Xia, Zhe-Gang Zhang, Xuan-Xuan Nian, Xue-Dan Li, Zheng Gong, Guo-Mei Zhang, Yang Le, Rong Zhou, Jia-You Zhang & Xiao-Ming Yang
Article: 2202278
Published online: 01 May 2023
AbstractforDevelopment of an mRNA vaccine against a panel of heterologous H1N1 seasonal influenza viruses using a consensus hemagglutinin sequence | Full Text | References | PDF (3 MB) | EPUB | Supplemental
  • 1648 Views
  • 1 CrossRef citations
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Research Article

Article
Probable airborne transmission of Burkholderia pseudomallei causing an urban outbreak of melioidosis during typhoon season in Hong Kong, China
Wing-Gi Wu, Marcus Ho-Hin Shum, Ivan Tak-Fai Wong, Kelvin Keru Lu, Lam-Kwong Lee, Jake Siu-Lun Leung, Hiu-Yin Lao, Annie Wing-Tung Lee, Pak-Ting Hau, Chloe Toi-Mei Chan, Harmen Fung-Tin Wong, Sharon Ka-Yee Fung, Sally Choi-Ying Wong, Iain Chi-Fung Ng, Timothy Ting-Leung Ng, Ning Chow, Alex Yat-Man Ho, Mei Fan Hung, Franklin Wang-Ngai Chow, Maureen Mo-Lin Wong, Wing-Kin To, Tommy Tsan-Yuk Lam, Kristine Shik Luk & Gilman Kit-Hang Siu
Article: 2204155
Published online: 01 May 2023
AbstractforProbable airborne transmission of Burkholderia pseudomallei causing an urban outbreak of melioidosis during typhoon season in Hong Kong, China | Full Text | References | PDF (3.2 MB) | EPUB | Supplemental
  • 1597 Views
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Coronaviruses

Review
Associations between SARS-CoV-2 infection and incidence of new chronic condition diagnoses: a systematic review
Lindsay A. Gaudet, Jennifer Pillay, Sabrina Saba, Dianne Zakaria, Nicholas Cheta, Hélène Gardiner, Larry Shaver, Jacqueline Middleton, Maria Tan, Ben Vandermeer & Lisa Hartling
Article: 2204166
Published online: 01 May 2023
AbstractforAssociations between SARS-CoV-2 infection and incidence of new chronic condition diagnoses: a systematic review | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 1664 Views
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Research Article

Article
Sputum pathogen spectrum and clinical outcomes of upper respiratory tract infection in bronchiectasis exacerbation: a prospective cohort study
Yan Huang, Chun-lan Chen, Lai-jian Cen, Hui-min Li, Zhen-hong Lin, Si-yu Zhu, Chong-yang Duan, Ri-lan Zhang, Cui-xia Pan, Xiao-fen Zhang, Xiao-xian Zhang, Zhen-feng He, Ming-xin Shi, Nan-shan Zhong & Wei-jie Guan
Article: 2202277
Published online: 08 May 2023
AbstractforSputum pathogen spectrum and clinical outcomes of upper respiratory tract infection in bronchiectasis exacerbation: a prospective cohort study | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
  • 1235 Views
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Coronaviruses

Article
Aggravated pneumonia and diabetes in SARS-CoV-2 infected diabetic mice
Qing Huang, Ran An, Haixuan Wang, Yun Yang, Cong Tang, Junbin Wang, Wenhai Yu, Yanan Zhou, Yongmei Zhang, Daoju Wu, Bai Li, Hao Yang, Shuaiyao Lu & Xiaozhong Peng
Article: 2203782
Published online: 01 May 2023
AbstractforAggravated pneumonia and diabetes in SARS-CoV-2 infected diabetic mice | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 1112 Views
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Research Article

Article
Effect of immunization during pregnancy and pre-existing immunity on diphtheria-tetanus-acellular pertussis vaccine responses in infants
Aapo Knuutila, Alex-Mikael Barkoff, Lauri Ivaska, Elina Tenhu, Johanna Teräsjärvi, Pieter van Gageldonk, Annemarie Buisman, Jussi Mertsola, Qiushui He & PERISCOPE consortium
Article: 2204146
Published online: 03 May 2023
AbstractforEffect of immunization during pregnancy and pre-existing immunity on diphtheria-tetanus-acellular pertussis vaccine responses in infants | Full Text | References | PDF (1.3 MB) | EPUB
  • 1064 Views
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Antimicrobial Agents

Article
A universal fluorescence polarization high throughput screening assay to target the SAM-binding sites of SARS-CoV-2 and other viral methyltransferases
Subodh Kumar Samrat, Qamar Bashir, Ran Zhang, Yiding Huang, Yuchen Liu, Xiangmeng Wu, Tyler Brown, Wei Wang, Y. George Zheng, Qing-Yu Zhang, Yin Chen, Zhong Li & Hongmin Li
Article: 2204164
Published online: 05 May 2023
AbstractforA universal fluorescence polarization high throughput screening assay to target the SAM-binding sites of SARS-CoV-2 and other viral methyltransferases | Full Text | References | PDF (3 MB) | EPUB | Supplemental
  • 1595 Views
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Letter

Letter
Severe infection by Vibrio anguillarum following a bite by a marine fish: a case report
Jing-Yue Hu, Xiao-Kai Zhang, Cheng-Qi Xin, Lei Zhang, Jian Kang & Ping Gong
Article: 2204145
Published online: 05 May 2023
AbstractforSevere infection by Vibrio anguillarum following a bite by a marine fish: a case report | Full Text | References | PDF (925.2 KB) | EPUB | Supplemental
  • 1002 Views
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Coronaviruses

Letter
An omicron-based vaccine booster elicits potent neutralizing antibodies against emerging SARS-CoV-2 variants in adults
Tao Li, Deyan Luo, Nianzhi Ning, Xin Wang, Liangyan Zhang, Xiaolan Yang, Deyu Li, Yakun Sun, Wenjing Yu, Wenjin Wei & Hui Wang
Article: 2207670
Published online: 10 Jun 2023
AbstractforAn omicron-based vaccine booster elicits potent neutralizing antibodies against emerging SARS-CoV-2 variants in adults | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 641 Views
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Research Article

Article
Mpox multi-antigen mRNA vaccine candidates by a simplified manufacturing strategy afford efficient protection against lethal orthopoxvirus challenge
Jiawei Zeng, Yao Li, Linrui Jiang, Ling Luo, Yue Wang, Hao Wang, Xiaonan Han, Jian Zhao, Guanglei Gu, Min Fang, Qingrui Huang & Jinghua Yan
Article: 2204151
Published online: 08 May 2023
AbstractforMpox multi-antigen mRNA vaccine candidates by a simplified manufacturing strategy afford efficient protection against lethal orthopoxvirus challenge | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 2175 Views
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Article
Respiratory microbiota imbalance in children with Mycoplasma pneumoniae pneumonia
Yacui Wang, Xiaoran Yu, Fang Liu, Xue Tian, Shuting Quan, Anxia Jiao, Xuemei Yang, Xi Zeng, Weiwei Jiao, Hui Qi, Fang Xu, Qinjing Li, Shuping Liu, Baoping Xu, Lin Sun & Adong Shen
Article: 2202272
Published online: 09 May 2023
AbstractforRespiratory microbiota imbalance in children with Mycoplasma pneumoniae pneumonia | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 1243 Views
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Article
The assessment on cross immunity with smallpox virus and antiviral drug sensitivity of the isolated mpox virus strain WIBP-MPXV-001 in China
Yan Zeng, Xiaoke Liu, Yuwei Li, Jia Lu, Qin Wu, Demiao Dan, Shiyun Lv, Fei Xia, Chunxia Hu, Jiali Li, Hao Zhang, Hongqiao Du, Rui Jia, Kai Duan, Zejun Wang, Xinguo Li & Xiaoming Yang
Article: 2208682
Published online: 11 May 2023
AbstractforThe assessment on cross immunity with smallpox virus and antiviral drug sensitivity of the isolated mpox virus strain WIBP-MPXV-001 in China | Full Text | References | PDF (2.3 MB) | EPUB
  • 1045 Views
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Antimicrobial Agents

Article
Discovery of a new chemical scaffold for the treatment of superbug Candida auris infections
Jie Tu, Tianbao Zhu, Qingwen Wang, Wanzhen Yang, Yahui Huang, Defeng Xu, Na Liu & Chunquan Sheng
Article: 2208687
Published online: 11 May 2023
AbstractforDiscovery of a new chemical scaffold for the treatment of superbug Candida auris infections | Full Text | References | PDF (3.2 MB) | EPUB | Supplemental
  • 1462 Views
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Coronaviruses

Article
Intranasal infection by SARS-CoV-2 Omicron variants can induce inflammatory brain damage in newly weaned hamsters
Can Li, Wenchen Song, Jasper Fuk-Woo Chan, Yanxia Chen, Feifei Liu, Zhanhong Ye, Alvin Hiu-Chung Lam, Jianpiao Cai, Andrew Chak-Yiu Lee, Bosco Ho-Yin Wong, Hin Chu, David Christopher Lung, Siddharth Sridhar, Honglin Chen, Anna Jin-Xia Zhang & Kwok-Yung Yuen
Article: 2207678
Published online: 12 Jun 2023
AbstractforIntranasal infection by SARS-CoV-2 Omicron variants can induce inflammatory brain damage in newly weaned hamsters | Full Text | References | PDF (9 MB) | EPUB | Supplemental
  • 1665 Views
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Article
Mutations in SARS-CoV-2 variant nsp6 enhance type-I interferon antagonism
Cody J. Bills, Hongjie Xia, John Yun-Chung Chen, Jason Yeung, Birte K. Kalveram, David Walker, Xuping Xie & Pei-Yong Shi
Article: 2209208
Published online: 14 May 2023
AbstractforMutations in SARS-CoV-2 variant nsp6 enhance type-I interferon antagonism | Full Text | References | PDF (2 MB) | EPUB | Supplemental
  • 1505 Views
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Research Article

Article
Fatal dermatophytic pseudomycetoma in a patient with non-HIV CD4 lymphocytopenia
Yinggai Song, Xiaowen Wang, Qian Li, Ruijun Zhang, Sybren de Hoog & Ruoyu Li
Article: 2208685
Published online: 17 May 2023
AbstractforFatal dermatophytic pseudomycetoma in a patient with non-HIV CD4 lymphocytopenia | Full Text | References | PDF (2.1 MB) | EPUB
  • 723 Views
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Coronaviruses

Article
MERS-CoV seroconversion amongst Malaysian Hajj pilgrims returning from the Middle East, 2016–2018: results from the MERCURIAL multiyear prospective cohort study
Jefree Johari, Robert D. Hontz, Brian L. Pike, Tupur Husain, Norhayati Rusli, Rozainanee Mohd-Zain, Vunjia Tiong, Hai-Yen Lee, Boon-Teong Teoh, Sing-Sin Sam, Chee-Sieng Khor, Shih-Keng Loong, Juraina Abd-Jamil, Siti-Sarah Nor'e, Hasmawati Yahaya, Naim Che-Kamaruddin, Jose A. Garcia-Rivera & Sazaly AbuBakar
Article: 2208678
Published online: 23 May 2023
AbstractforMERS-CoV seroconversion amongst Malaysian Hajj pilgrims returning from the Middle East, 2016–2018: results from the MERCURIAL multiyear prospective cohort study | Full Text | References | PDF (965.5 KB) | EPUB | Supplemental
  • 923 Views
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Article
The unreversible reduced but persistent activated NK and CD8+ T cells in severe/critical COVID-19 during omicron pandemic in China
Ling Qin, Xinmin Duan, Jay Zengjun Dong, Yue Chang, Yang Han, Yan Li, Wei Jiang, Hongwei Fan, Xiufeng Hou, Wei Cao, Huadong Zhu & Taisheng Li
Article: 2208679
Published online: 15 May 2023
AbstractforThe unreversible reduced but persistent activated NK and CD8+ T cells in severe/critical COVID-19 during omicron pandemic in China | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 1530 Views
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Research Article

Article
Pteropine orthoreoviruses use cell surface heparan sulphate as an attachment receptor
Chee Wah Tan, Akshamal M. Gamage, Wee Chee Yap, Leon Jia Wei Tang, Yuan Sun, Xing-Lou Yang, Alyssa Pyke, Kaw Bing Chua & Lin-Fa Wang
Article: 2208683
Published online: 16 May 2023
AbstractforPteropine orthoreoviruses use cell surface heparan sulphate as an attachment receptor | Full Text | References | PDF (3.6 MB) | EPUB | Supplemental
  • 997 Views
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Open Access
Article
Global mpox research in the light of the current outbreak: demands, drivers, and obstacles
Doris Klingelhöfer, Markus Braun, David A. Groneberg & Dörthe Brüggmann
Article: 2210696
Published online: 15 May 2023
AbstractforGlobal mpox research in the light of the current outbreak: demands, drivers, and obstacles | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
  • 637 Views
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Coronaviruses

Article
Orthogonal dual reporter-based gain-of-signal assay for probing SARS-CoV-2 3CL protease activity in living cells: inhibitor identification and mutation investigation
Zhu-Chun Bei, Huanhuan Yu, Hong Wang, Qingyun Li, Baogang Wang, Dongna Zhang, Likun Xu, Liangliang Zhao, Shuwei Dong & Yabin Song
Article: 2211688
Published online: 15 May 2023
AbstractforOrthogonal dual reporter-based gain-of-signal assay for probing SARS-CoV-2 3CL protease activity in living cells: inhibitor identification and mutation investigation | Full Text | References | PDF (3.5 MB) | EPUB | Supplemental
  • 1050 Views
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Research Article

Article
Porcine deltacoronavirus resists antibody neutralization through cell-to-cell transmission
Sijin Xia, Wenwen Xiao, Xuerui Zhu, Shusen Liao, Jiahui Guo, Junwei Zhou, Shaobo Xiao, Puxian Fang & Liurong Fang
Article: 2207688
Published online: 17 May 2023
AbstractforPorcine deltacoronavirus resists antibody neutralization through cell-to-cell transmission | Full Text | References | PDF (5.4 MB) | EPUB
  • 1009 Views
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Coronaviruses

Article
Waning effectiveness against COVID-19-related hospitalization, severe complications, and mortality with two to three doses of CoronaVac and BNT162b2: a case–control study
Vincent Ka Chun Yan, Eric Yuk Fai Wan, Xuxiao Ye, Anna Hoi Ying Mok, Francisco Tsz Tsun Lai, Celine Sze Ling Chui, Xue Li, Carlos King Ho Wong, Philip Hei Li, Tiantian Ma, Simon Qin, Chak Sing Lau, Ian Chi Kei Wong & Esther Wai Yin Chan
Article: 2209201
Published online: 18 May 2023
AbstractforWaning effectiveness against COVID-19-related hospitalization, severe complications, and mortality with two to three doses of CoronaVac and BNT162b2: a case–control study | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
  • 1181 Views
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Influenza infections

Article
Reciprocal enhancement of SARS-CoV-2 and influenza virus replication in human pluripotent stem cell-derived lung organoids
Min Jung Kim, Sumi Kim, Heeyeon Kim, Dayeon Gil, Hyeong-Jun Han, Rajesh K. Thimmulappa, Jang-Hoon Choi & Jung-Hyun Kim
Article: 2211685
Published online: 27 May 2023
AbstractforReciprocal enhancement of SARS-CoV-2 and influenza virus replication in human pluripotent stem cell-derived lung organoids | Full Text | References | PDF (3.7 MB) | EPUB | Supplemental
  • 1566 Views
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Coronaviruses

Impaired potency of neutralizing antibodies against cell–cell fusion mediated by SARS-CoV-2
Qian Wang, Andre Yanchen Yeh, Yicheng Guo, Hiroshi Mohri, Jian Yu, David D. Ho & Lihong Liu
Article: 2210237
Published online: 25 May 2023
AbstractforImpaired potency of neutralizing antibodies against cell–cell fusion mediated by SARS-CoV-2 | Full Text | References | PDF (1.6 MB) | EPUB | Supplemental
  • 866 Views
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Open Access
Article
Post-exposure prophylaxis with SA58 (anti-SARS-COV-2 monoclonal antibody) nasal spray for the prevention of symptomatic COVID-19 in healthy adult workers: a randomized, single-blind, placebo-controlled clinical study*
Rui Song, Gang Zeng, Jianxing Yu, Xing Meng, Xiaoyou Chen, Jing Li, Xiaoliang Xie, Xiaojuan Lian, Zhiyun Zhang, Yunlong Cao, Weidong Yin & Ronghua Jin
Article: 2212806
Published online: 25 May 2023
AbstractforPost-exposure prophylaxis with SA58 (anti-SARS-COV-2 monoclonal antibody) nasal spray for the prevention of symptomatic COVID-19 in healthy adult workers: a randomized, single-blind, placebo-controlled clinical study* | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
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Influenza infections

Article
Cell-intrinsic genomic reassortment of pandemic H1N1 2009 and Eurasian avian-like swine influenza viruses results in potentially zoonotic variants
Verónica A. Ferrando, Marcel E. Friedrich, Shrey Gandhi, Alexander Mellmann, Dörthe Masemann, Anmari Christersson, Darisuren Anhlan, Linda Brunotte, Monika Stoll, Timm Harder, Martin Beer, Yvonne Boergeling & Stephan Ludwig
Article: 2212809
Published online: 25 May 2023
AbstractforCell-intrinsic genomic reassortment of pandemic H1N1 2009 and Eurasian avian-like swine influenza viruses results in potentially zoonotic variants | Full Text | References | PDF (2.9 MB) | EPUB | Supplemental
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Article
Mixed selling of different poultry species facilitates emergence of public-health-threating avian influenza viruses
Zhen Wang, Hongkui Li, Yuhan Li, Zhuanli Wu, Hui Ai, Ming Zhang, Libin Rong, Michael L. Blinov, Qi Tong, Litao Liu, Honglei Sun, Juan Pu, Wenhai Feng, Jinhua Liu & Yipeng Sun
Article: 2214255
Published online: 25 May 2023
AbstractforMixed selling of different poultry species facilitates emergence of public-health-threating avian influenza viruses | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
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Research Article

Article
Immune reconstitution efficacy after combination antiretroviral therapy in male HIV-1 infected patients with homosexual and heterosexual transmission
You Ge, Ying Zhou, Yahong Liu, Jing Lu, Tao Qiu, Ling-En Shi, Zhi Zhang, Haiyang Hu, Pingmin Wei & Gengfeng Fu
Article: 2214250
Published online: 13 Jun 2023
AbstractforImmune reconstitution efficacy after combination antiretroviral therapy in male HIV-1 infected patients with homosexual and heterosexual transmission | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
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Review Article

Review Article
Predictors of mortality from extended-spectrum beta-lactamase-producing Enterobacteriaceae bacteremia
Hiroki Namikawa, Waki Imoto, Koichi Yamada, Yoshihiro Tochino, Yukihiro Kaneko, Hiroshi Kakeya & Taichi Shuto
Article: 2217951
Published online: 05 Jun 2023
AbstractforPredictors of mortality from extended-spectrum beta-lactamase-producing Enterobacteriaceae bacteremia | Full Text | References | PDF (2.5 MB) | EPUB
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Research Article

Article
Rift Valley fever virus modulates apoptosis and immune response during infection of human astrocytes
Jordan Quellec, Aurélie Pédarrieu, Camille Piro-Mégy, Jonathan Barthelemy, Yannick Simonin, Sara Salinas & Catherine Cêtre-Sossah
Article: 2207672
Published online: 22 Jun 2023
AbstractforRift Valley fever virus modulates apoptosis and immune response during infection of human astrocytes | Full Text | References | PDF (3.6 MB) | EPUB | Supplemental
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Article
Comparative analysis of whole genomes and transcriptomes of Microsporum canis from invasive dermatophytosis and tinea capitis
Ruojun Wang, Weixia Liu, Xiao Liu, Zhe Wan, G. Sybren de Hoog, Ruoyu Li & Yinggai Song
Article: 2219346
Published online: 08 Jun 2023
AbstractforComparative analysis of whole genomes and transcriptomes of Microsporum canis from invasive dermatophytosis and tinea capitis | Full Text | References | PDF (2 MB) | EPUB
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Article
Circulation of Lassa virus across the endemic Edo-Ondo axis, Nigeria, with cross-species transmission between multimammate mice
Adetunji Samuel Adesina, Akinlabi Oyeyiola, Adeoba Obadare, Joseph Igbokwe, Chukwuyem Abejegah, Patience Akhilomen, Umaru Bangura, Danny Asogun, Ekaete Tobin, Olufemi Ayodeji, Omolaja Osoniyi, Chris Davis, Emma C. Thomson, Meike Pahlmann, Stephan Günther, Elisabeth Fichet-Calvet & Ayodeji Olayemi
Article: 2219350
Published online: 08 Jun 2023
AbstractforCirculation of Lassa virus across the endemic Edo-Ondo axis, Nigeria, with cross-species transmission between multimammate mice | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
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Hepatitis

Article
Unexpected rise in the circulation of complex HBV variants enriched of HBsAg vaccine-escape mutations in HBV genotype-D: potential impact on HBsAg detection/quantification and vaccination strategies
Lorenzo Piermatteo, Stefano D’Anna, Ada Bertoli, Maria Bellocchi, Luca Carioti, Lavinia Fabeni, Mohammad Alkhatib, Simone La Frazia, Miriam Lichtner, Claudio Mastroianni, Giuseppe De Sanctis, Massimo Marignani, Caterina Pasquazzi, Nerio Iapadre, Giustino Parruti, Giuseppina Cappiello, Jacopo Vecchiet, Vincenzo Malagnino, Sandro Grelli, Francesca Ceccherini-Silbertein, Massimo Andreoni, Loredana Sarmati, Valentina Svicher & Romina Salpini
Article: 2219347
Published online: 08 Jun 2023
AbstractforUnexpected rise in the circulation of complex HBV variants enriched of HBsAg vaccine-escape mutations in HBV genotype-D: potential impact on HBsAg detection/quantification and vaccination strategies | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
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Research Article

Article
The first suspected disseminated Hormographiella aspergillata infection in China, diagnosed using metagenomic next-generation sequencing: a case report and literature review
Qian Wang, Yinggai Song, Dongmei Han, Hong Cai, Qiuhong Yan, Wei Liu, Hengxiang Wang, Xiaoli Zheng, Li Ding & Xiaoying Yuan
Article: 2220581
Published online: 11 Jun 2023
AbstractforThe first suspected disseminated Hormographiella aspergillata infection in China, diagnosed using metagenomic next-generation sequencing: a case report and literature review | Full Text | References | PDF (2.4 MB) | EPUB
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Coronaviruses

Serological evidence of SARS-CoV-2 infection in dromedary camels and domestic bovids in Oman
Ihab El Masry, Salim Al Makhladi, Mohsin Al Abdwany, Afrah Al Subhi, Hatim Eltahir, Samuel Cheng, Malik Peiris, Emma Gardner, Sophie Von Dobschuetz, Baba Soumare, Madhur Dhingra, Keith Sumption & Markos Tibbo
Article: 2220577
Published online: 12 Jun 2023
AbstractforSerological evidence of SARS-CoV-2 infection in dromedary camels and domestic bovids in Oman | Full Text | References | PDF (488.8 KB) | EPUB | Supplemental
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Antimicrobial Agents

Article
A bacteriophage cocktail delivered in feed significantly reduced Salmonella colonization in challenged broiler chickens
Anisha M. Thanki, Steven Hooton, Natasha Whenham, Michael G. Salter, Mike R. Bedford, Helen V. Masey O'Neill & Martha R. J. Clokie
Article: 2217947
Published online: 20 Jun 2023
AbstractforA bacteriophage cocktail delivered in feed significantly reduced Salmonella colonization in challenged broiler chickens | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
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Coronaviruses

Article
The ecology of viruses in urban rodents with a focus on SARS-CoV-2
Adam M. Fisher, George Airey, Yuchen Liu, Matthew Gemmell, Jordan Thomas, Eleanor G. Bentley, Mark A. Whitehead, William A. Paxton, Georgios Pollakis, Steve Paterson & Mark Viney
Article: 2217940
Published online: 12 Jun 2023
AbstractforThe ecology of viruses in urban rodents with a focus on SARS-CoV-2 | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
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Research Article

Article
Temporal and coevolutionary analyses reveal the events driving the emergence and circulation of human mamastroviruses
Lester J. Perez, Kenn Forberg, Gavin A. Cloherty & Michael G. Berg
Article: 2217942
Published online: 12 Jun 2023
AbstractforTemporal and coevolutionary analyses reveal the events driving the emergence and circulation of human mamastroviruses | Full Text | References | PDF (3.1 MB) | EPUB | Supplemental
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Influenza infections

Article
Diverse infectivity, transmissibility, and pathobiology of clade 2.3.4.4 H5Nx highly pathogenic avian influenza viruses in chickens
Jung-Hoon Kwon, Kateri Bertran, Dong-Hun Lee, Miria Ferreira Criado, Lindsay Killmaster, Mary J. Pantin-Jackwood & David E. Swayne
Article: 2218945
Published online: 12 Jun 2023
AbstractforDiverse infectivity, transmissibility, and pathobiology of clade 2.3.4.4 H5Nx highly pathogenic avian influenza viruses in chickens | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
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Retraction

Retraction
Statement of Retraction: A novel Fas-binding outer membrane protein and lipopolysaccharide of Leptospira interrogans induce macrophage apoptosis through the Fas/FasL-caspase-8/-3 pathway
Article: 2240210
Published online: 07 Aug 2023
CitationforStatement of Retraction: A novel Fas-binding outer membrane protein and lipopolysaccharide of Leptospira interrogans induce macrophage apoptosis through the Fas/FasL-caspase-8/-3 pathway | Full Text | PDF (163.5 KB) | EPUB
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