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Research Article

Circulating fetuin-A in patients with pancreatic cancer: a hospital-based case-control study

, , , , , , , & show all
Pages 660-666
Received 25 Aug 2014
Accepted 04 Oct 2014
Published online: 27 Oct 2014

Abstract

Context: A proteomic analysis has proposed fetuin-A (alpha-2-HS-glycoprotein) as a new potential marker for pancreatic cancer (PC).

Objective: Circulating fetuin-A levels in patients with PC.

Methods: Serum fetuin-A was measured in 81 cases with PC and 81 matched controls before the initiation of any treatment.

Results: Serum fetuin-A was not independently associated with the presence of PC. Although there was a trend with higher fetuin-A levels across PC stages, comparisons of fetuin-A in patients within different PC prognostic stages revealed no differences.

Conclusions: Circulating fetuin-A was similar between patients and controls and was not associated with the disease severity.

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