Objective: To analyse the physical growth of a representative school population sample from the Jequitinhonha Valley, Minas Gerais, Brazil, in comparison with the reference proposed by the Centre for Disease Control and Prevention (CDC-2000).

Methods: The sample was composed of 5100 individuals (2730 girls and 2370 boys), aged 6–18 years. Body weight-for-age and height-for-age percentiles were obtained using the LMS method. Statistical and graphical comparisons were made with the corresponding percentiles of the CDC-2000 reference, estimated using the same method.

Results: Overall, the calculated values of the L (asymmetry) and the S (variability) parameters were quite similar to the CDC-2000 reference values. However, M (median) was substantially different from the reference used in the study, mainly in schoolchildren over 12–13 years of age of both genders. The magnitude of the deficits of height-for-age and body weight-for-age observed in the schoolchildren from the Jequitinhonha Valley, Minas Gerais, Brazil, varied from 4 to 6 cm and from 3 to 6 kg, respectively.

Conclusion: The body weight-for-age and height-for-age percentiles of schoolchildren population in the Jequitinhonha Valley, Minas Gerais, Brazil differed substantially from those referenced.