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Natural Product Research

Formerly Natural Product Letters
Volume 33, 2019 - Issue 2
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Research Articles

New alkylamide from the stems of Zanthoxylum nitidum

, , , , , & show all
Pages 153-161
Received 05 Oct 2017
Accepted 04 Feb 2018
Published online: 19 Feb 2018

Abstract

A new alkylamide, named (2E,6E,8E)-N-(2-methylpropyl)-10-oxo-2,6,8-decatrienamide (1), together with 22 known compounds (2–23), were isolated from the stems of Zanthoxylum nitidum. Their structures were elucidated by spectroscopic methods, including 1D and 2D NMR spectroscopy. The isolated compounds exhibited slightly antioxidant activities through DPPH and ABTS radical scavenging assays but showed no antibacterial activity against Streptococcus mutans ATCC2517, a dental caries causing bacteria.

Graphical abstract

Acknowledgements

The authors also would like to thank Associate professor Chanita Ponglimanont for helpful suggestion. We would like to thank the Scientific Equipment Center, Prince of Songkla University for the MS analysis.

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