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Original Articles

Chronic Fatigue Syndrome Versus Sudden Onset Myalgic Encephalomyelitis

, , , &
Pages 62-77
Published online: 13 Jan 2015
 

A revised sudden onset case definition for Myalgic Encephalomyelitis (ME) has been developed (Jason, Damrongvachiraphan, etal., 2012 Jason, L. A., Damrongvachiraphan, D., Hunnell, J., Bartgis, L., Brown, A., Evans, M., & Brown, M. (2012). Myalgic Encephalomyelitis: Case definitions. Autonomic Control of Physiological State and Function, 1, 114. Retrieved from http://www.ashdin.com/journals/ACPSF/K110601.pdf[Crossref] [Google Scholar]) based on past case definitions. In a prior study, Jason, Brown, and colleagues (2012 Jason, L. A., Unger, E. R., Dimitrakoff, J. D., Fagin, A. P., Houghton, M., Cook, D., … Snell, C. (2012). Minimum data elements for research reports on CFS. Brain, Behavior and Immunity, 26, 401406. PMID: 22306456[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) compared patients recruited using the 1994 case definition of chronic fatigue syndrome (CFS) to contrast those meeting criteria for the revised ME criteria. They found that this revised ME case definition identified patients with more functional impairments and physical, mental, and cognitive problems than those meeting the CFS criteria. The study by Jason, Brown, etal. (2012 Jason, L. A., Unger, E. R., Dimitrakoff, J. D., Fagin, A. P., Houghton, M., Cook, D., … Snell, C. (2012). Minimum data elements for research reports on CFS. Brain, Behavior and Immunity, 26, 401406. PMID: 22306456[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) only selected individuals who first met the CFS criteria, and it only relied on one Chicago-based data set. The current study replicated this comparison with two distinct data sets with different case ascertainment methods. Results indicate that the ME criteria identified a group of patients with more functional disabilities as well as more severe post-exertional malaise symptoms.

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