Screening, Brief Intervention, and Referral to Treatment (SBIRT) is an evidence-based protocol that addresses both moderate-risk and high-risk substance use problems for individuals. In an urban college’s master’s and bachelor’s social work programs with 218 students, SBIRT training was introduced into core course curricula, with many students subsequently using SBIRT in their field placements. Evaluation of the initiative demonstrated increases in the students’ knowledge and favorable attitudes regarding working with substance using clients. Students’ ratings of the usefulness and effectiveness of SBIRT were high. In response to studies indicating the lack of preparedness of graduating social work students to work with substance users, this study demonstrated the effectiveness of SBIRT training to educate students to work with this population.