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Journal of Asian Natural Products Research

Volume 17, 2015 - Issue 7
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Articles

Four new alkylamides from the roots of Zanthoxylum nitidum

Ling-Juan Zhu College of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China
,
Ming Ren College of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China
,
Tie-Chui Yang China Resources of Sanjiu Medical & Pharmaceutical Co., Ltd, Shenzhen 518110, China
,
Cheng Qiao College of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China
,
Bei-Bei Chen China Resources of Sanjiu Medical & Pharmaceutical Co., Ltd, Shenzhen 518110, China
,
Zheng-Zhou Han China Resources of Sanjiu Medical & Pharmaceutical Co., Ltd, Shenzhen 518110, China
,
Shu-Hong Wang Shenzhen Institute For Drug Control, Shenzhen 518057, China
,
Ping Wen Shenzhen Institute For Drug Control, Shenzhen 518057, China
&
Xue Zhang College of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, ChinaCorrespondencesyzxalice@163.com
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Pages 711-716
Received 12 Feb 2015
Accepted 04 May 2015
Published online: 22 Jun 2015
 
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Abstract

Phytochemical investigation on the roots of Zanthoxylum nitidum led to the isolation of four new unsaturated alkylamides, zanthoxylumamides A–D. Their structures were established via the detailed spectroscopic analyses.

Acknowledgements

We are grateful to Prof. Mao-Xiang Lai at Guangxi Institute of Chinese Medicine & Pharmaceutical Science, for the botanical collection and identification. We also thank Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University for the optical rotation and HR-ESI-MS measurements.

Disclosure statement

No potential conflict of interest was reported by the author(s).

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