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ABSTRACT
Objective: Numerous epidemiological studies have reported relevance of morbidity and mortality from cardiovascular diseases with short-term exposure to environmental temperature. In this study, we examined the hypothesis between temperature indices and hospital admission because of cardiovascular diseases.
Methods: The daily number of CVDs was obtained from all hospitals of the Sabzevar city. A semi-parametric generalized additive model (GAM) following a quasi-Poisson distribution with distributed lag non-linear model (dlnm) was selected as a modeling framework for time-series analysis.
Results: The overall CVD risk comparing the 1st percentile and the 99th percentile relative to the mean temperature (at lag 0) was 1.33 (95% CI, 1.11: 1.61), and 1.34 (95% CI, 1.10: 1.64), respectively. For all indicators, the extremely cold effects persisted for the initial 7 days.
Conclusions: Our results suggest that extremely cold and extremely hot temperatures increase the relative risk of cardiovascular diseases.
Contributors
DM participated in the study design, analysis, and wrote the manuscript. DM also conducted data collection. MJZS also participated in the preparation of the draft of the paper, revised the draft of the manuscript, and supervised the project. MJZS also conducted data analysis. All authors participated in the development of the manuscript and data interpretation. MZZ participated in the study design, interpretation of findings, and also wrote the manuscript. All authors read and approved the final manuscript.
Ethics approval and consent to participate
The study was approved by the Ethics Committee of the Shahid Sadoughi University of Medical Sciences (Ethics Committee approval number: IR.SSU.SPH.REC.1396.121)
Supplementary material
Supplemental data for this article can be accessed here.