Immigrant businesses have become an increasingly important component in the US economy. However, very few studies have systematically examined the role of immigrant businesses in community development, except for some cases in established immigrant gateways such as New York and Miami. In this study, we explore how immigrant businesses are shaping physical, cultural, social, economic, and political landscapes in their local communities in the emerging immigrant gateway of Charlotte, North Carolina. Focusing on the case of a multiethnic retail corridor, we find that, as active place-makers, immigrant businesses have transformed deteriorating and abandoned street fronts into vibrant and well-frequented urban environments conducive for further development. Through a systematic approach to understanding the place-making process of immigrant businesses, findings from this study call for more in-depth integration of immigrant and ethnic economies in local policies and planning strategies for neighborhood revitalization. These findings are particularly pertinent in the context of the continuous ethnic diversification of our neighborhoods and cities.