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Ultrastructural Pathology

Volume 7, 1984 - Issue 4
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Original Article

A Comparative Ultrastructural Study of Virions in Human Pre-AIDS and Simian AIDS

Thomas F.C.S. Warner Wisconsin Regional Primate Research Center and Departments of Pathology and Laboratory Medicine, University of Wisconsin, Madison, Wisconsin, 53715–1299
,
M. R. C. Path Wisconsin Regional Primate Research Center and Departments of Pathology and Laboratory Medicine, University of Wisconsin, Madison, Wisconsin, 53715–1299
,
Hideo Uno Wisconsin Regional Primate Research Center and Departments of Pathology and Laboratory Medicine, University of Wisconsin, Madison, Wisconsin, 53715–1299
,
Carol Gabel Departments of Pathology and Laboratory Medicine, University of Wisconsin, Madison, Wisconsin, 53715–1299
&
Che-Chung Tsai Regional Primate Center, University of Washington, Seattle, Washington
Pages 251-258
Published online: 10 Jul 2009
 
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Original Article

A Comparative Ultrastructural Study of Virions in Human Pre-AIDS and Simian AIDS

Abstract

Virions resembling the AIDS-associated retroviruses HTLV-III and LAV were identified between pseudo-pods of dendritic reticulum cells in lymph nodes from 3 patients with prodromal AIDS. The virions are morphologically distinguishable from HTLV-I and HTLV-II and also from D-type retroviruses that are associated with the simian acquired immune deficiency syndrome. Budding forms resembling incomplete nucleoids of maturing D-type retrovirus were found in neutrophils in a lymph node from another patient with prodromal AIDS. The significance of these structures is unknown.

 

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