The Scandinavian Society for Clinical Chemistry and NORDKEM have had a number of joint efforts to facilitate the optimal performance and use of clinical laboratory investigations. A new committee (DOOKK or Diagnosis and Organ Oriented Committee for Clinical Chemistry) was established (in 1984) in order to improve collaboration between clinicians and laboratory physicians. In particular, the approach has been to work out recommendations for different clinical working hypotheses concerning restricted diagnoses or organ-specific problems. The aim of our project (“Hemolysis”) was to create a rational scheme for the use of clinical chemical and hematological laboratory investigations in suspected or known cases of hemolysis.