This study presents a method to model population densities by using image texture statistics of semi-variance. In a case study of the City of Austin, Texas, we first selected sample census blocks of the same land use to build population models by land use. Regression analyses were conducted to infer the relationship between block population densities and image texture statistics of the semi-variance. We then applied the population models to an area of 251 blocks to estimate populations for within-blocks land-use areas while maintaining census block populations. To assess the proposed method, the same analysis was performed while census block-group populations were maintained, and the aggregated block populations were compared with original census block populations. We also tested a conventional land-use-based dasymetric mapping method with pre-calculated population densities for land uses. The results show that our approach, which is based on initial land-use stratification and further image-texture statistical modeling of population, has higher accuracy statistics than the conventional land-use-based dasymetric mapping method.