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Original Articles

Synthesis of Biomimetic Analogs of Neomycin B: Potential Inhibitors of the HIV RNA Rev Response Element

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Pages 283-295
Published online: 24 Sep 2006

Abstract

The aminoglycosidic antibiotic, neomycin B, is an inhibitor of the binding of Rev to RRE. This paper reports on the synthesis of analogs of neomycin B as potential anti-HIV compounds designed to function as inhibitors of Rev/RRE binding.

 

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