Much has been written about family-centered care (FCC) as a best practice for children with special health care needs. There is limited research on the extent to which children with autism spectrum disorders and their families receive FCC or to delineate what elements of FCC are particularly important to meet their needs. We will examine the extant literature on FCC as a collaborative and empowering practice, the perceptions of parents of children with disabilities about FCC in both the healthcare and education fields, and will review the limited research on the specific needs of families that have a child with ASD. As part of this review, we will identify future directions for research and practice in caring for children with ASD and their families.