This paper describes a systems analysis approach to human performance in office work systems. The approach, integrating both micro- and macroergonomic aspects, provides a process for more comprehensive, systematic solutions. This systems approach is designed to assess office workers' performance and effectiveness problems within technology intensive office work environments and provide realistic solutions for improving performance. The approach incorporates micro- and macroergonomic factors to adequately address the performance and stress and health-related problems associated with modern office work systems. The seven step approach consists of: defining the problems; setting the objectives and developing alternatives; modelling alternatives; evaluating alternatives; selecting an alternative; planning for implementation; and evaluation, feedback and modification. A detailed schematic presentation of these steps is provided. Solutions or alternatives are proposed to minimize the identified problem factors and to improve performance and the quality of work life.