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Self‐Assembly of PEG and Diester Copolymers: Effect of PEG Length, Linker, Concentration and Temperature
- DOI:
- 10.1080/10601320500229087
pages 1523-1528
Available online: 21 Aug 2006Abstract
The formation of micelles in a solvent that is selective for one of the blocks is one of the most important and useful properties of block copolymers. Recently, we have synthesized copolymers of polyethylene glycol and various dimethyl esters, which self‐assemble into nano micellar aggregates in aqueous media. These nano micelles are very effective in solubilizing otherwise insoluble drugs. The structure, interaction and size of these nano micelles are very important and critical to design an efficient drug delivery system. In the present work, we have studied the effect of hydrophilic block, PEG length, linker, concentration and temperature on these nano micellar structures and interactions by static light scattering techniques.
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- Citation information:
- Available online: 21 Aug 2006
Author affiliations
- a Institute for NanoScience and Engineering Technology and Center for Advanced Materials, Department of Chemistry, University of Massachusetts, Lowell, MA, USA
- b Bioorganic Laboratory, Department of Chemistry, University of Delhi, Delhi, India
- c Division of Agricultural Chemicals, Indian Agricultural Research Institute, New Delhi, India
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- 2010 Impact Factor: 0.816 (©2011 Thomson Reuters, 2010 Journal Citation Reports®)
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