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A new cytotoxic homoisoflavonoid from Dracaena cambodiana
- DOI:
- 10.1080/10286020802674962
pages 192-195
Available online: 13 Feb 2009Abstract
A new homoisoflavonoid, named cambodianol (1), together with the two known flavanes, (2S)-7,3′-dihydroxy-4′-methoxy-8-methylflavane (2) and (2R)-7,4′-dihydroxy-8-methylflavane (3), were isolated from the stems of Dracaena cambodiana. Their structures were determined based on HR-ESI-MS and spectroscopic techniques (UV, IR, 1D-, and 2D-NMR). Compound 1 exhibited significant cytotoxic activities against K562 and SGC-7901 with the IC50 values of 1.4 and 2.9 μg/ml, respectively.
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- Citation information:
- Available online: 13 Feb 2009
Author affiliations
- a Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, China
- b State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China
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- 2010 Impact Factor: 0.706 (2011 Thomson Reuters, Journal Citation Reports)
- © 2010 Thomson Reuters, 2009 Journal Citation Reports ®
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